Citations for
1CX3CR1
CX3CR1 as a respiratory syncytial virus receptor in pediatric human lung.
Anderson CS, Chu CY, Wang Q, Mereness JA, Ren Y, Donlon K, Bhattacharya S, Misra RS, Walsh EE, Pryhuber GS, Mariani TJ.
Pediatr Res. Apr;87(5):862-867. doi: 10.1038/s41390-019-0677-0. Epub 2019 Nov 14 2020
2CX3CR1
Fractalkine/CX3CR1 is involved in the cross-talk between neuron and glia in neurological diseases.
Luo P, Chu SF, Zhang Z, Xia CY, Chen NH.
Brain Res Bull. Mar;146:12-21. doi: 10.1016/j.brainresbull.2018.11.017. Epub 2018 Nov 26 2019
3CX3CL1, CX3CR1
Evidence for a protective role of the CX3CL1/CX3CR1 axis in a model of amyotrophic lateral sclerosis.
Liu C, Hong K, Chen H, Niu Y, Duan W, Liu Y, Ji Y, Deng B, Li Y, Li Z, Wen D, Li C.
Biol Chem. Apr 24;400(5):651-661. doi: 10.1515/hsz-2018-0204 2019
4CX3CR1
The Role of the Microglial Cx3cr1 Pathway in the Postnatal Maturation of Retinal Photoreceptors.
Jobling AI, Waugh M, Vessey KA, Phipps JA, Trogrlic L, Greferath U, Mills SA, Tan ZL, Ward MM, Fletcher EL.
J Neurosci. May 16;38(20):4708-4723. doi: 10.1523/JNEUROSCI.2368-17.2018. Epub 2018 Apr 18 2018
5CX3CL1, CX3CR1
Ischemia-induced Neuronal Cell Death Is Mediated by Chemokine Receptor CX3CR1.
Wang J, Gan Y, Han P, Yin J, Liu Q, Ghanian S, Gao F, Gong G, Tang Z.
Sci Rep. Jan 11;8(1):556. doi: 10.1038/s41598-017-18774-0 2018
6CX3CL1, CX3CR1, MAPT
Absence of CX3CR1 impairs the internalization of Tau by microglia.
Bolós M, Llorens-Martín M, Perea JR, Jurado-Arjona J, Rábano A, Hernández F, Avila J.
Mol Neurodegener. Aug 15;12(1):59. doi: 10.1186/s13024-017-0200-1 2017
7CX3CL1, CX3CR1
Analysis of the Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Traumatic Brain and Spinal Cord Injury: Insight into Recent Advances in Actions of Neurochemokine Agents.
Poniatowski ŁA, Wojdasiewicz P, Krawczyk M, Szukiewicz D, Gasik R, Kubaszewski Ł, Kurkowska-Jastrzębska I.
Mol Neurobiol. Apr;54(3):2167-2188. doi: 10.1007/s12035-016-9787-4. Epub 2016 Mar 1 2017
8CX3CL1, CX3CR1
CX3CL1/CX3CR1 in Alzheimer's Disease: A Target for Neuroprotection.
Chen P, Zhao W, Guo Y, Xu J, Yin M.
Biomed Res Int. 2016:8090918. doi: 10.1155/2016/8090918. Epub 2016 Jun 27 2016
9CX3CL1, CX3CR1
Microglial phagocytosis and activation underlying photoreceptor degeneration is regulated by CX3CL1-CX3CR1 signaling in a mouse model of retinitis pigmentosa.
Zabel MK, Zhao L, Zhang Y, Gonzalez SR, Ma W, Wang X, Fariss RN, Wong WT.
Glia Sep;64(9):1479-91. doi: 10.1002/glia.23016. Epub 2016 Jun 17 2016
10CX3CR1
Functional classification of memory CD8(+) T cells by CX3CR1 expression.
Böttcher JP, Beyer M, Meissner F, Abdullah Z, Sander J, Höchst B, Eickhoff S, Rieckmann JC, Russo C, Bauer T, Flecken T, Giesen D, Engel D, Jung S, Busch DH, Protzer U, Thimme R, Mann M, Kurts C, Schultze JL, Kastenmüller W, Knolle PA.
Nat Commun. Sep 25;6:8306. doi: 10.1038/ncomms9306 2015
11CX3CL1, CX3CR1
Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway.
Apostolakis S, Spandidos D.
Acta Pharmacol Sin. Oct;34(10):1251-6. doi: 10.1038/aps.2013.92. Epub 2013 Aug 26 2013
12CCR2, CX3CR1
Arteriolar and venular remodeling are differentially regulated by bone marrow-derived cell-specific CX3CR1 and CCR2 expression.
Meisner JK, Song J, Price RJ.
PLoS One 7(9):e46312. doi: 10.1371/journal.pone.0046312. Epub 2012 Sep 24. 2012
13CX3CR1
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.
Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, Ransohoff RM, Gan L.
J Biol Chem 286(37):32713-22. Epub 2011 Jul 19. 2011
14CX3CL1, CX3CR1
CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung.
Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, Langelot M, Lacoeuille Y, Hessel E, Coffman R, Magnan A, Dombrowicz D, Glaichenhaus N, Julia V.
Nat Med 16(11):1305-12. Epub 2010 Oct 31. 2010
15CCL26, CCR3, CX3CL1, CX3CR1, IL13, IL4
Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.
Nakayama T, Watanabe Y, Oiso N, Higuchi T, Shigeta A, Mizuguchi N, Katou F, Hashimoto K, Kawada A, Yoshie O.
J Immunol. Dec 1;185(11):6472-9. doi: 10.4049/jimmunol.0904126. Epub 2010 Oct 25 2010
16CX3CR1
Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling.
Liang KJ, Lee JE, Wang YD, Ma W, Fontainhas AM, Fariss RN, Wong WT.
Invest Ophthalmol Vis Sci. 50(9):4444-51. 2009
17CX3CL1, CX3CR1
Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption.
Koizumi K, Saitoh Y, Minami T, Takeno N, Tsuneyama K, Miyahara T, Nakayama T, Sakurai H, Takano Y, Nishimura M, Imai T, Yoshie O, Saiki I.
J Immunol 183(12):7825-31. Epub . 2009
18CX3CR1, GZMB, IGFBP7, IL2RB, KIR3DL2, PAM, PRF1, S1PR5, SH2D1B, SPON2, ZBTB16
Gene expression changes in children with autism.
Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR.
Genomics 91(1):22-9. Epub 2007 Nov 14. 2008
19CX3CL1, CX3CR1
Functional adhesiveness of the CX3CL1 chemokine requires its aggregation. Role of the transmembrane domain.
Hermand P, Pincet F, Carvalho S, Ansanay H, Trinquet E, Daoudi M, Combadière C, Deterre P.
J Biol Chem 283(44):30225-34. Epub 2008 Aug 25. 2008
20ACE, ARMD1, ARMD2, ARMD3, ARMD7, ARMD8, ARMDA, ARMDC, ARMS2, CFH, CX3CR1, FBLN5, HTRA1, MMP9, SOD2, VEGFA
Progress in defining the molecular biology of age related macular degeneration.
Lotery A, Trump D.
Hum Genet 122(3-4):219-36. Epub 2007 Jul 21. No abstract available. 2007
21CX3CR1
A CX3CR1 genotype associated with retinal vasculitis in patients in the United Kingdom.
Wallace GR, Vaughan RW, Kondeatis E, Mathew R, Chen Y, Graham EM, Stanford MR.
Invest Ophthalmol Vis Sci 47(7):2966-70. 2006
22CX3CR1, CX3CL1
The CX3CL1-CX3CR1 system and psoriasis.
Plant D, Young HS, Watson RE, Worthington J, Griffiths CE.
Exp Dermatol 15(11):900-3. 2006
23CX3CR1
Association study between the CX3CR1 gene and asthma.
Tremblay K, Lemire M, Provost V, Pastinen T, Renaud Y, Sandford AJ, Laviolette M, Hudson TJ, Laprise C.
Genes Immun 7(8):632-9. Epub 2006 Nov 2. 2006
24CX3CR1
Adverse associations between CX3CR1 polymorphisms and risk of cardiovascular or cerebrovascular disease.
Lavergne E, Labreuche J, Daoudi M, Debre P, Cambien F, Deterre P, Amarenco P, Combadiere C; GENIC Investigators.
Arterioscler Thromb Vasc Biol 25(4):847-53. Epub 2005 Jan 27. 2005
25CX3CR1
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance.
Niess, J. H.; Brand, S.; Gu, X.; Landsman, L.; Jung, S.; McCormick, B. A.; Vyas, J. M.; Boes, M.; Ploegh, H. L.; Fox, J. G.; Littman, D. R.; Reinecker, H.-C.
Science 307: 254-258 2005
26CX3CR1
The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration.
Tuo J, Smith BC, Bojanowski CM, Meleth AD, Gery I, Csaky KG, Chew EY, Chan CC.
FASEB J 18(11):1297-9. Epub 2004 Jun 18. 2004
27CX3CR1
The fractalkine receptor CX3CR1 is a key mediator of atherogenesis.
Cybulsky MI, Hegele RA.
J Clin Invest 111(8):1118-20. No abstract available. 2003
28CX3CR1
Two novel fully functional isoforms of CX3CR1 are potent HIV coreceptors.
Garin A, Tarantino N, Faure S, Daoudi M, Lécureuil C, Bourdais A, Debré P, Deterre P, Combadiere C.
J Immunol. 171(10):5305-12. 2003
29CX3CR1
Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.
Lesnik, P.; Haskell, C. A.; Charo, I. F
J. Clin. Invest. 111: 333-340 2003
30CX3CR1
Expression of the fractalkine receptor (CX3CR1) in human kidney diseases.
Segerer S, Hughes E, Hudkins KL, Mack M, Goodpaster T, Alpers CE.
Kidney Int 62(2):488-95. 2002
31CX3CR1
Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease.
Moatti D, Faure S, Fumeron F, Amara Mel-W, Seknadji P, McDermott DH, Debre P, Aumont MC, Murphy PM, de Prost D, Combadiere C.
Blood 97(7):1925-8. 2001
32CX3CL1, CX3CR1
Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.
Mizoue LS, Sullivan SK, King DS, Kledal TN, Schwartz TW, Bacon KB, Handel TM.
J Biol Chem 276(36):33906-14. 2001
33CX3CR1
CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein.
Tripp, R. A.; Jones, L. P.; Haynes, L. M.; Zheng, H.; Murphy, P. M.; Anderson, L. J.
Nature Immun. 2: 732-738 2001
34CX3CR1
Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival.
Meucci O, Fatatis A, Simen AA, Miller RJ.
Proc Natl Acad Sci U S A 97(14):8075-80. 2000
35CX3CR1
Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1.
Faure S, Meyer L, Costagliola D, Vaneensberghe C, Genin E, Autran B, Delfraissy JF, McDermott DH, Murphy PM, Debre P, Theodorou I, Combadiere C.
Science 287(5461):2274-7. 2000
36CX3CR1, CX3CL1
Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1.
Mizoue LS, et al.
Biochemistry 38(5):1402-14. 1999
37CCR1, CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CCR9, CX3CR1, CXCR1, CXCR2, CXCR3, CXCR4, XCR1
Intracellular signalling pathways induced by chemokines in natural killer cells.
Maghazachi AA.
Cell Signal 11(6):385-90. Review 1999
38ACKR2, CCR4, CCR9, CX3CR1, XCR1
Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome.
Maho A, Bensimon A, Vassart G, Parmentier M.
Cytogenet Cell Genet 87(3-4):265-268. 1999
39CX3CR1
Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia.
Harrison JK, et al.
Proc Natl Acad Sci U S A 95 : 10896-10901. 1998
40CX3CR1
Molecular cloning and characterization of a cDNA, CHEMR1, encoding a chemokine receptor with a homology to the human C-C chemokine receptor, CCR-4.
Youn BS, Kim SH, Lyu MS, Kozak CA, Taub DD, Kwon BS.
Blood 89(12):4448-60. 1997
41CX3CR1
Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion.
Imai T, et al.
Cell 91 : 521-530. 1997
42CX3CR1, CX3CL1
A new class of membrane-bound chemokine with a CX3C motif.
Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A, Schall TJ.
Nature 385(6617):640-4. 1997
43CX3CR1
Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor.
Samson M, et al.
Eur J Immunol 26 : 3021-3028. 1996
44CX3CR1
Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like gene.
Combadiere C, et al.
DNA Cell Biol 14 : 673-680. 1995
45CX3CR1
The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues.
Raport CJ, et al.
Gene 163(2):295-9 1995