Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

TNS4

contributors: mct/ - updated : 28-08-2015

HGNC name	tensin 4
HGNC id	24352

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   or nul in prostate cancers and prostate cancer cell lines tumoral     --over   in 70 p100 of pancreatic cancers

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	its expression is of prognostic significance in colorectal cancer, delineating a TNS4-ILK pathway controlling cell motility and possibly promoting metastasis
Therapy target
	System Type Disorder Pubmed cancer metastases   anti-metastatic therapies may benefit from restoring or preserving tensin expression in primary tumors

ANIMAL & CELL MODELS