| 1 | DLC1, MET, TNS4, XPO1
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| Identification of subcellular targeting sequences of Cten reveals its role in cell proliferation.
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| Hong SY, Shih YP, Lo A, Lo SH.
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| Biochim Biophys Acta Mol Cell Res 1866(3):450-458. doi: 10.1016/j.bbamcr.2018.10.008. Epub 2018 Oct 13.
2019
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| 2 | TNS4
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| CTEN Prolongs Signaling by EGFR through Reducing Its Ligand-Induced Degradation.
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| Hong SY, Shih YP, Li T, Carraway KL 3rd, Lo SH.
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| Cancer Res 73(16):5266-76. doi: 10.1158/0008-5472.CAN-12-4441. Epub 2013 Jun 17.
2013
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| 3 | TNS4
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| C-terminal tensin-like gene functions as an oncogene and promotes cell motility in pancreatic cancer.
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| Al-Ghamdi S, Cachat J, Albasri A, Ahmed M, Jackson D, Zaitoun A, Guppy N, Otto WR, Alison MR, Kindle KB, Ilyas M.
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| Pancreas 42(1):135-40. doi: 10.1097/MPA.0b013e3182557ceb.
2013
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| 4 | DLC1, TNS3, TNS4
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| Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation.
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| Cao X, Voss C, Zhao B, Kaneko T, Li SS.
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| Proc Natl Acad Sci U S A 109(5):1455-60. doi: 10.1073/pnas.1114368109. Epub 2012 Jan 17. Erratum in: Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4708.
2012
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| 5 | TNS4
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| Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.
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| Al-Ghamdi S, Albasri A, Cachat J, Ibrahem S, Muhammad BA, Jackson D, Nateri AS, Kindle KB, Ilyas M.
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| PLoS One 6(6):e20919. doi: 10.1371/journal.pone.0020919. Epub 2011 Jun 16.
2011
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| 6 | TNS4
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| Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer.
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| Albasri A, Al-Ghamdi S, Fadhil W, Aleskandarany M, Liao YC, Jackson D, Lobo DN, Lo SH, Kumari R, Durrant L, Watson S, Kindle KB, Ilyas M.
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| Oncogene 30(26):2997-3002. doi: 10.1038/onc.2011.26. Epub 2011 Feb 21.
2011
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| 7 | TNS4
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| Transcriptional profiling identifies TNS4 function in epithelial tubulogenesis.
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| Kwon SH, Nedvetsky PI, Mostov KE.
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| Curr Biol 21(2):161-6. doi: 10.1016/j.cub.2010.12.037. Epub 2011 Jan 13.
2011
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| 8 | TNS1, TNS2, TNS3, TNS4
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| Individual domains of Tensin2 exhibit distinct subcellular localisations and migratory effects.
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| Hafizi S, Sernstad E, Swinny JD, Gomez MF, Dahlbäck B.
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| Int J Biochem Cell Biol 42(1):52-61. Epub 2009 Sep 9.PMID: 19747564 2010
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| 9 | TNS1, TNS2, TNS3, TNS4
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| Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.
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| Martuszewska D, Ljungberg B, Johansson M, Landberg G, Oslakovic C, Dahlbäck B, Hafizi S.
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| PLoS One 4(2):e4350. doi: 10.1371/journal.pone.0004350. Epub 2009 Feb 4. 2009
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| 10 | TNS3, TNS4
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| A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.
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| Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y.
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| Nat Cell Biol 9(8):961-9. Epub 2007 Jul 22. 2007
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| 11 | STARD13, DLC1, STARD8, TNS4
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| START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology.
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| Kawai K, Kiyota M, Seike J, Deki Y, Yagisawa H.
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| Biochem Biophys Res Commun 364(4):783-9. Epub 2007 Oct 17. 2007
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| 12 | TNS4
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| Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer.
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| Lo SH, Lo TB.
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| Cancer Res 62(15):4217-21. 2002
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