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FLASH GENE
Symbol PTRH2 contributors: mct - updated : 17-01-2013
HGNC name peptidyl-tRNA hydrolase 2
HGNC id 24265
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
conferred cancer cells with enhanced anoikis resistance, adhesive and migratory properties in vitro and specifically potentiated tumor metastasis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
therapeutic importance of restoring PTRH2 expression in cancer cells to circumvent metastasis at least in part through inhibition of the Erk pathway
ANIMAL & CELL MODELS