Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CD276

contributors: mct - updated : 04-05-2016

HGNC name	CD276 antigen
HGNC id	19137

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in acute myeloid leukemia tumoral     --over   in oral squamous cell carcinoma (OSCC), and its overexpression correlated with larger tumor size, advanced clinical stage, and low survival rate in OSCC patients tumoral     --over   in the pancreatic cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer hemopathy   CD276 silencing inhibits tumor progression of mantle cell lymphoma and enhances chemosensitivity cancer lung   is a promising target for new immunotherapeutic strategies in MM, with particular emphasis in the epithelial variant (malignant mesothelioma (MM)

ANIMAL & CELL MODELS