Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

IL8

contributors: mct - updated : 27-10-2018

HGNC name	interleukin 8
HGNC id	6025

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in ulcerative colitis and Crohn's disease and in osteoarthritis cartilage tumoral     --over   in mesothelioma tumoral     --over   colorectal cancer (CRC), and is associated with poor prognosis constitutional     --over   significantly higher IL8 levels in Alzheimer disease brain tissue lysates as compared to those of age-matched controls

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive colon important therapeutic target in colorectal cancer

ANIMAL & CELL MODELS