Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol IL8 contributors: mct - updated : 27-10-2016
HGNC name interleukin 8
HGNC id 6025
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in ulcerative colitis and Crohn's disease and in osteoarthritis cartilage
tumoral     --over  
in mesothelioma
tumoral     --over  
colorectal cancer (CRC), and is associated with poor prognosis
constitutional     --over  
significantly higher IL8 levels in Alzheimer disease brain tissue lysates as compared to those of age-matched controls
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerdigestivecolon
important therapeutic target in colorectal cancer
ANIMAL & CELL MODELS