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FLASH GENE

Symbol

THSD3

contributors: - updated : 28-02-2006

HGNC name	thrombospondin, type I domain-containing 3
HGNC id	23176

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - splicing 2942 63.9 571 - Rossi variant 2 - splicing 3047 - 483 - Rossi an additional exon at the 5' end initiating translation from a downstream start codon variant 3 - splicing 2596 - 292 - Rossi lacks an in-frame coding exon

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system placenta     highly

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text

placenta

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	an hydrophobic signal peptide
	17 putative glycosylation sites
	a thrombospondin type I repeat (TSR) domain
	an AMOP domain

conjugated

GlycoP

HOMOLOGY

Homologene

FAMILY

isthmin family

CATEGORY

adhesion

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION

may be involved in adhesion processes

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS