Symbol
| LHX6
| contributors: mct - updated : 07-07-2015
|
HGNC name
| LIM homeobox 6
|
HGNC id
| 21735
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
by hypermethylation in head and neck squamous cell carcinoma and colon carcinoma | constitutional
|  
|  
| --low
|  
|
in schizophrenia | tumoral
|  
|  
| --low
|  
|
by hypermethylation in lung cancer | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| amelogenin and ameloblastin expression is reduced and/or delayed in the Lhx6 null mice, potentially resulting from defects in dentin deposition and ameloblast differentiation |