Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

RSPO3

contributors: mct/npt/pgu - updated : 18-12-2023

HGNC name	R-spondin 3 homolog (Xenopus laevis)
HGNC id	20866

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in a TP53-deficient mammary epithelial cell line

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive colon as a candidate target for therapy in patients with colorectal cancer harbouring RSPO3 fusions cancer reproductive breast RSPO3 itself is likely a valuable therapeutic target in breast cancer

ANIMAL & CELL MODELS