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FLASH GENE
Symbol HYDIN contributors: mct - updated : 13-10-2012
HGNC name hydrocephalus inducing
HGNC id 19368
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinethyroid   highly
Reproductivemale systemtestis  highly
Visualeyeretina  highly
cell lineage
cell lines
fluid/secretion
at STAGE
Text eye
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • potential central pair protein required for ciliary motility
  • axonemal protein, involved in growth and microtubule motility
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ICS19
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • mice with Hydin defects develop lethal hydrocephalus, and hydrocephalus is caused by a central pair defect impairing ciliary motility and fluid transport in the brain