Symbol
| TFAP2C
| contributors: mct - updated : 04-04-2016
|
HGNC name
| transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
|
HGNC id
| 11744
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
in breast cancer | constitutional
|  
| deletion
|  
|  
|
results in early embryonic loss because of failure in placental development ![](pubmed.jpg) | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| |
|
System | Type | Disorder | Pubmed |
cancer | reproductive | breast | ![](pubmed.jpg) |
may be a viable therapeutic target in breast cancer | cancer | reproductive | breast | ![](pubmed.jpg) |
therapeutic target in the design of new drug treatments for breast cancer |
| | |
| Tcfap2c-deficient mice display a defect in trophectoderm development ![](pubmed.jpg) |