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FLASH GENE
Symbol TFAP2C contributors: mct - updated : 04-04-2016
HGNC name transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
HGNC id 11744
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in breast cancer
constitutional   deletion    
results in early embryonic loss because of failure in placental development
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerreproductivebreast
may be a viable therapeutic target in breast cancer
cancerreproductivebreast
therapeutic target in the design of new drug treatments for breast cancer
ANIMAL & CELL MODELS
  • Tcfap2c-deficient mice display a defect in trophectoderm development