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FLASH GENE

Symbol

CGAS

contributors: mct - updated : 30-10-2018

HGNC name	cyclic GMP-AMP synthase
HGNC id	21367

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed immunology autoimmune   inhibition of CGAS may lead to prevention and treatment of some human autoimmune diseases caused by self-DNA

ANIMAL & CELL MODELS

mice deficient in Cgas were more susceptible to lethality caused by infection with M. tuberculosis