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FLASH GENE
Symbol NAP1L4 contributors: npt/ - updated : 01-07-2006
HGNC name nucleosome assembly protein 1-like 4
HGNC id 7640
PROTEIN
PHYSICAL PROPERTIES acid
STRUCTURE
motifs/domains
  • potential nuclear localization motif
  • two clusters of highly acidic residues
    • HOMOLOGY
    Homologene
    FAMILY
  • nucleosome assembly protein (NAP) family
    • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text localized mainly to the cytoplasm and a minor population of them was suggested to be in the nucleus (Okuwaki 2010)
    basic FUNCTION
  • with NAP1L1 mediated nucleosome formation (Okuwaki 2010)
  • play overlapping roles in transport and deposition of histone H2A-H2B or H2A variants-H2B dimers on chromatin and nonoverlapping roles in nucleosome disassembly (Okuwaki 2010)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • core and linker histones
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS