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FLASH GENE
Symbol NAP1L4 contributors: npt/ - updated : 01-07-2006
HGNC name nucleosome assembly protein 1-like 4
HGNC id 7640
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  highly
 mouthtongue  highly
 salivary gland   highly
Lymphoid/Immunespleen   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES acid
STRUCTURE
motifs/domains
  • potential nuclear localization motif
  • two clusters of highly acidic residues
  • HOMOLOGY
    Homologene
    FAMILY
  • nucleosome assembly protein (NAP) family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text localized mainly to the cytoplasm and a minor population of them was suggested to be in the nucleus (Okuwaki 2010)
    basic FUNCTION
  • with NAP1L1 mediated nucleosome formation (Okuwaki 2010)
  • play overlapping roles in transport and deposition of histone H2A-H2B or H2A variants-H2B dimers on chromatin and nonoverlapping roles in nucleosome disassembly (Okuwaki 2010)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • core and linker histones
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS