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FLASH GENE

Symbol

NLRP6

contributors: mct/pgu - updated : 18-08-2012

HGNC name	NLR family, pyrin domain containing 6
HGNC id	22944

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Nlrp6 inflammasome-deficient mice were characterized by spontaneous intestinal hyperplasia, inflammatory cell recruitment
	Nlrp6-deficient mice were highly resistant to infection with the bacterial pathogens Listeria monocytogenes, Salmonella typhimurium and Escherichia coli, and infected Nlrp6-deficient mice had increased numbers of monocytes and neutrophils in circulation