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FLASH GENE
Symbol NLRP6 contributors: mct/pgu - updated : 18-08-2012
HGNC name NLR family, pyrin domain containing 6
HGNC id 22944
ANIMAL & CELL MODELS
  • Nlrp6 inflammasome-deficient mice were characterized by spontaneous intestinal hyperplasia, inflammatory cell recruitment
  • Nlrp6-deficient mice were highly resistant to infection with the bacterial pathogens Listeria monocytogenes, Salmonella typhimurium and Escherichia coli, and infected Nlrp6-deficient mice had increased numbers of monocytes and neutrophils in circulation