Symbol
| EPOR
| contributors: mct - updated : 17-01-2018
|
HGNC name
| erythropoietin receptor
|
HGNC id
| 3416
|
corresponding disease(s)
|
ECYT1
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
| gain of function
|
activated cell proliferation pathways in melanoma cells and resulted in increased cell proliferation and resistance to hypoxia and cisplatin treatment | |
Variant & Polymorphism
|
| |
Candidate gene
| unlikely involved in Diamond-Blackfan anemia |
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cardiovascular | aquired | | |
EPO/EPOR is a novel therapeutic target in cardiovascular disease |
| | |
| macrophage-specific Epor(-/-) mice developed lupus-like symptoms, and interference in EPO signaling ameliorated the disease progression in lupus-like mice |