| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
| fusion
|
|
|
|
|
with HMGA2 in the salivary gland pleomorphic adenoma |
| tumoral
|
|
| --low
|
|
|
in salivary gland pleomorphic adenoma in progression |
| tumoral
|
|
| --low
|
|
in mesothelioma 72-fold compared to normal tissue, and WIF1 promoter methylation is a common event in mesothelioma  |
| tumoral
|
|
| --low
|
|
|
in 76p100 of examined osteosarcoma cases, with promoter methylation ( |
| tumoral
|
|
| --low
|
|
|
is frequently downregulated or silenced by promoter methylation in the carcinogenesis of Oral submucous fibrosis (OSF) |
| tumoral
|
|
| --low
|
|
|
downregulated by promoter methylation and is an important mechanism of aberrant WNT/CTNNB1 pathway activation in astrocytoma pathogenesis |
| tumoral
|
|
| --low
|
|
|
by epigenetic gene silencing is an important mechanism of WNT activation in cervical oncogenesis |
