| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| constitutional
|
|
| --low
|
|
with epithelial differentiation  | | constitutional
|
|
| --over
|
| |
in epidermal keratinocytes deregulates multiple signaling pathways associated with increased growth rate, anchorage-independent cell survival, and the development of skin tumors | | tumoral
|
|
| --over
|
| |
in a series of epithelial malignancies, including gastric cancer, squamous cell carcinomas, melanoma, metastatic prostate cancer | | tumoral
|
|
| --low
|
| |
were significantly decreased in oral squamous cell carcinoma cells that expressed SNAIl | | tumoral
|
|
| --other
|
| |
aberrantly expressed in human skin carcinomas | | tumoral
|
|
|
|
| |
silencing of DSG2 resulted in loss of cell cohesion and enhanced migration, and invasion of pancreatic adenocarcinoma cells | |
