Symbol
| CDK1
| contributors: mct/ - updated : 27-12-2021
|
HGNC name
| cyclin-dependent kinase 1
|
HGNC id
| 1722
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
|  
| loss of function
|
cells lacking CDK1 cannot proliferate but instead enter a senescent state and survive in culture medium | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| reliable molecular biomarker for the diagnosis of prostate carcinoma | Therapy target
|
System | Type | Disorder | Pubmed |
cancer | | | |
potential of CDK1 inhibitors in cancer therapy |
| | |