| 1 | CDK1, DDX21, WDR5
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| DDX21 Interacts with WDR5 to Promote Colorectal Cancer Cell Proliferation by Activating CDK1 Expression.
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| Lu P, Yu Z, Wang K, Zhai Y, Chen B, Liu M, Xu P, Li F, Zhao Q.
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| J Cancer. Feb 28;13(5):1530-1539. doi: 10.7150/jca.69216. 2022
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| 2 | CDK1, E2F1, ZNF655
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| ZNF655 accelerates progression of pancreatic cancer by promoting the binding of E2F1 and CDK1.
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| Shao Z, Li C, Wu Q, Zhang X, Dai Y, Li S, Liu X, Zheng X, Zhang J, Fan H.
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| Oncogenesis. Aug 4;11(1):44. doi: 10.1038/s41389-022-00418-2. 2022
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| 3 | CDK1, DEPDC1B
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| Overexpressed DEPDC1B contributes to the progression of hepatocellular carcinoma by CDK1
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| Dang XW, Pan Q, Lin ZH, Wang HH, Li LH, Li L, Shen DQ, Wang PJ.
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| Aging (Albany NY). May 25;13(16):20094-20115. doi: 10.18632/aging.203016. Epub 2021 May 25. 2021
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| 4 | CDK1, LONRF1, RACK1, RPL18, RPL30, SEC61A1
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| Identification of crucial genes and pathways associated with prostate cancer in multiple databases
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| Guo H, Zhang Z, Wang Y, Xue S.
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| J Int Med Res. Jun;49(6):3000605211016624. doi: 10.1177/03000605211016624. 2021
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| 5 | CDK1, NFATC1
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| Inhibition of osteoclasts differentiation by CDC2-induced NFATc1 phosphorylation.
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| Kim HM, He L, Lee S, Park C, Kim DH, Han HJ, Han J, Hwang J, Cha-Molstad H, Lee KH, Ko SK, Jang JH, Ryoo IJ, Blenis J, Lee HG, Ahn JS, Kwon YT, Soung NK, Kim BY.
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| Bone. Feb;131:115153. doi: 10.1016/j.bone.2019.115153. Epub 2019 Nov 12 2020
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| 6 | CDK1, TIAL1
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| TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress
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| Lafarga V, Sung HM, Haneke K, Roessig L, Pauleau AL, Bruer M, Rodriguez-Acebes S, Lopez-Contreras AJ, Gruss OJ, Erhardt S, Mendez J, Fernandez-Capetillo O, Stoecklin G.
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| EMBO Rep Jan;20(1):e46224. doi: 10.15252/embr.201846224. Epub 2018 Dec 11. 2019
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| 7 | CCNA1, CDK1, PLK1, PPP1R12A
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| Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.
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| Dumitru AMG, Rusin SF, Clark AEM, Kettenbach AN, Compton DA.
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| Elife 6. pii: e29303. doi: 10.7554/eLife.29303.
2017
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| 8 | CDK1, VGLL4
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| Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity
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| Zeng Y, Stauffer S, Zhou J, Chen X, Chen Y, Dong J.
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| J Biol Chem. Sep 8;292(36):15028-15038. doi: 10.1074/jbc.M117.796284. Epub 2017 Jul 24. 2017
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| 9 | CDK1, DES
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| Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.
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| Makihara H, Inaba H, Enomoto A, Tanaka H, Tomono Y, Ushida K, Goto M, Kurita K, Nishida Y, Kasahara K, Goto H, Inagaki M.
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| Biochem Biophys Res Commun 478(3):1323-9. doi: 10.1016/j.bbrc.2016.08.122. Epub 2016 Aug 23.
2016
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| 10 | CDK1, DNA2, EXO1, WRN
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| CDK1 phosphorylates WRN at collapsed replication forks.
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| Palermo V, Rinalducci S, Sanchez M, Grillini F, Sommers JA, Brosh RM Jr, Zolla L, Franchitto A, Pichierri P.
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| Nat Commun 7:12880. doi: 10.1038/ncomms12880.
2016
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| 11 | CDK1, PTPRF
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| LAR protein tyrosine phosphatase regulates focal adhesions through CDK1 .2016 . PMID:
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| Sarhan AR, Patel TR, Cowell AR, Tomlinson MG, Hellberg C, Heath JK, Cunningham DL, Hotchin NA.
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| J Cell Sci. Aug 1;129(15):2962-71. doi: 10.1242/jcs.191379. Epub 2016 Jun 27 2016
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| 12 | CDK1, PLK1, TP53
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| Polo-like kinase 1 inhibits DNA damage response during mitosis.
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| Benada J, Burdová K, Lidak T, von Morgen P, Macurek L.
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| Cell Cycle 14(2):219-31. doi: 10.4161/15384101.2014.977067.
2015
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| 13 | CDK1, NSUN2
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| NSun2 Promotes Cell Growth via Elevating Cyclin-Dependent Kinase 1 Translation.
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| Xing J, Yi J, Cai X, Tang H, Liu Z, Zhang X, Martindale JL, Yang X, Jiang B, Gorospe M, Wang W.
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| Mol Cell Biol 35(23):4043-52. doi: 10.1128/MCB.00742-15. Epub 2015 Sep 21.
2015
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| 14 | CDK1, CTDP1, ENSA, MASTL
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| PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.
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| Hégarat N, Vesely C, Vinod PK, Ocasio C, Peter N, Gannon J, Oliver AW, Novák B, Hochegger H.
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| PLoS Genet. Jan;10(1):e1004004. doi: 10.1371/journal.pgen.1004004. Epub 2014 Jan 2. Erratum in: PLoS Genet. 2014 Feb;10(2):e1004259. 2014
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| 15 | CDK1, CDKN3
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| The tumor suppressor CDKN3 controls mitosis.
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| Nalepa G, Barnholtz-Sloan J, Enzor R, Dey D, He Y, Gehlhausen JR, Lehmann AS, Park SJ, Yang Y, Yang X, Chen S, Guan X, Chen Y, Renbarger J, Yang FC, Parada LF, Clapp W.
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| J Cell Biol 201(7):997-1012. doi: 10.1083/jcb.201205125. Epub 2013 Jun 17. Erratum in: J Cell Biol. 2013 Aug 19;202(4):717.
2013
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| 16 | CDK1, MYT1, WEE1
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| The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.
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| Chow JP, Poon RY.
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| Oncogene 32(40):4778-88. doi: 10.1038/onc.2012.504. Epub 2012 Nov 12. 2013
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| 17 | CDK1, PIN1, PLK1, SEPTIN9
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| Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis.
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| Estey MP, Di Ciano-Oliveira C, Froese CD, Fung KY, Steels JD, Litchfield DW, Trimble WS.
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| J Biol Chem 288(42):30075-86. doi: 10.1074/jbc.M113.474932. Epub 2013 Aug 29. 2013
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| 18 | CDK1, CDK4, CDK5, UCHL1
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| Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity.
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| Kabuta T, Mitsui T, Takahashi M, Fujiwara Y, Kabuta C, Konya C, Tsuchiya Y, Hatanaka Y, Uchida K, Hohjoh H, Wada K.
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| J Biol Chem 288(18):12615-26. doi: 10.1074/jbc.M112.435701. Epub 2013 Mar 29.
2013
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| 19 | CDK1, PBK
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| In silico structural and functional analysis of the human TOPK protein by structure modeling and molecular dynamics studies.
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| Kirubakaran P, Karthikeyan M, Singh KhD, Nagamani S, Premkumar K.
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| J Mol Model 19(1):407-19. doi: 10.1007/s00894-012-1566-1. Epub 2012 Sep 1.
2013
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| 20 | AURKB, CDCA5, CDK1, WAPL
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| Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.
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| Nishiyama T, Sykora MM, Huis in 't Veld PJ, Mechtler K, Peters JM.
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| Proc Natl Acad Sci U S A 110(33):13404-9. doi: 10.1073/pnas.1305020110. Epub 2013 Jul 30.
2013
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| 21 | CDK1
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| Increased CDK1 activity determines the timing of kinetochore-microtubule attachments in meiosis I
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| Davydenko O, Schultz RM, Lampson MA.
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| J Cell Biol. Jul 22;202(2):221-9. doi: 10.1083/jcb.201303019. Epub 2013 Jul 15. 2013
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| 22 | CDK1, POU5F1
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| Cdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectoderm.
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| Li L, Wang J, Hou J, Wu Z, Zhuang Y, Lu M, Zhang Y, Zhou X, Li Z, Xiao W, Zhang W.
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| FEBS Lett 586(23):4100-7. doi: 10.1016/j.febslet.2012.10.030. Epub 2012 Oct 26.
2012
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| 23 | CCNA2, CDK1, CDK2
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| Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.
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| Diril MK, Ratnacaram CK, Padmakumar VC, Du T, Wasser M, Coppola V, Tessarollo L, Kaldis P.
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| Proc Natl Acad Sci U S A 109(10):3826-31. doi: 10.1073/pnas.1115201109. Epub 2012 Feb 21.
2012
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| 24 | CDK1, CLASP2, PLK1
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| Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments.
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| Maia AR, Garcia Z, Kabeche L, Barisic M, Maffini S, Macedo-Ribeiro S, Cheeseman IM, Compton DA, Kaverina I, Maiato H.
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| J Cell Biol 199(2):285-301. doi: 10.1083/jcb.201203091. Epub 2012 Oct 8.
2012
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| 25 | CDK1, NEK6, NEK7, NUP98
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| Phosphorylation of Nup98 by multiple kinases is crucial for NPC disassembly during mitotic entry.
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| Laurell E, Beck K, Krupina K, Theerthagiri G, Bodenmiller B, Horvath P, Aebersold R, Antonin W, Kutay U.
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| Cell 144(4):539-50.
2011
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| 26 | CDK1, CEP250, KIF11
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| Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.
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| Smith E, Hégarat N, Vesely C, Roseboom I, Larch C, Streicher H, Straatman K, Flynn H, Skehel M, Hirota T, Kuriyama R, Hochegger H.
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| EMBO J 30(11):2233-45. Epub 2011 Apr 26.
2011
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| 27 | CDK1, CEP63
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| Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance.
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| Löffler H, Fechter A, Matuszewska M, Saffrich R, Mistrik M, Marhold J, Hornung C, Westermann F, Bartek J, Krämer A.
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| Cancer Res 71(6):2129-39.
2011
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| 28 | CDK1, CDK2, CDK5, DNMT1
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| Phosphorylation of human DNMT1: implication of cyclin-dependent kinases.
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| Lavoie G, St-Pierre Y.
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| Biochem Biophys Res Commun 409(2):187-92. Epub 2011 May 1.
2011
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| 29 | CDK1
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| Dynamics of Cdk1 substrate specificity during the cell cycle.
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| Kőivomägi M, Valk E, Venta R, Iofik A, Lepiku M, Morgan DO, Loog M.
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| Mol Cell 42(5):610-23.
2011
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| 30 | AURKB, CDK1
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| Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics.
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| Nakajima Y, Cormier A, Tyers RG, Pigula A, Peng Y, Drubin DG, Barnes G.
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| J Cell Biol 194(1):137-53. Epub 2011 Jul 4.
2011
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| 31 | CDK1, RAD51, RBBP8
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| Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.
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| Peterson SE, Li Y, Chait BT, Gottesman ME, Baer R, Gautier J.
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| J Cell Biol 194(5):705-20.
2011
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| 32 | BCL2L11, CCNB1, CDK1
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| Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis.
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| Mac Fhearraigh S, Mc Gee MM.
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| Cell Cycle 10(22):3886-96. Epub 2011 Nov 15. 2011
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| 33 | CDK1, NCAPD3
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| The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II.
|
| Abe S, Nagasaka K, Hirayama Y, Kozuka-Hata H, Oyama M, Aoyagi Y, Obuse C, Hirota T.
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| Genes Dev 25(8):863-74. doi: 10.1101/gad.2016411.
2011
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| 34 | CCNB1, CDK1
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| Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity.
|
| Matthess Y, Raab M, Sanhaji M, Lavrik IN, Strebhardt K.
|
| Mol Cell Biol ol Cell Biol. 2010 Oct 11. [Epub ahead of print]PMID: 20937773 2010
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| 35 | CDK1, CDK2, EZH2
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| Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2.
|
| Chen S, Bohrer LR, Rai AN, Pan Y, Gan L, Zhou X, Bagchi A, Simon JA, Huang H.
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| Nat Cell Biol 2010 Oct 10. [Epub ahead of print]PMID: 20935635 2010
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| 36 | CDK1, CDK2
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| Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase.
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| Maeshima K, Iino H, Hihara S, Funakoshi T, Watanabe A, Nishimura M, Nakatomi R, Yahata K, Imamoto F, Hashikawa T, Yokota H, Imamoto N.
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| Nat Struct Mol Biol 17(9):1065-71. Epub 2010 Aug 15.PMID: 20711190 2010
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| 37 | AURKA, CDK1, PLK1
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| Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
|
| Van Horn RD, Chu S, Fan L, Yin T, Du J, Beckmann R, Mader M, Zhu G, Toth J, Blanchard K, Ye XS.
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| J Biol Chem 285(28):21849-57. Epub 2010 May 5.PMID: 20444701 2010
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| 38 | CCNB1, CDK1
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| Activation of cyclin B1-Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis.
|
| Gavet O, Pines J.
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| J Cell Biol 189(2):247-59.PMID: 20404109 2010
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| 39 | CDK1, ZSWIN7
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| Srs2 plays a critical role in reversible G2 arrest upon chronic and low doses of UV irradiation via two distinct homologous recombination-dependent mechanisms in postreplication repair-deficient cells.
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| Hishida T, Hirade Y, Haruta N, Kubota Y, Iwasaki H.
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| Mol Cell Biol 30(20):4840-50. Epub 2010 Aug 16. 2010
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| 40 | CCNB1, CDK1
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| Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis.
|
| Gavet O, Pines J.
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| Dev Cell 18(4):533-43.
2010
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| 41 | CDK1, KMT2E
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| Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry.
|
| Liu J, Wang XN, Cheng F, Liou YC, Deng LW.
|
| J Biol Chem 285(27):20904-14. doi: 10.1074/jbc.M109.098558. Epub 2010 May 3.
2010
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| 42 | CDK1, MYT1
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| A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry.
|
| Ruiz EJ, Vilar M, Nebreda AR.
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| Curr Biol 20(8):717-23. doi: 10.1016/j.cub.2010.02.050. Epub 2010 Apr 1.
2010
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| 43 | CDK1
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| The 3Ms of central spindle assembly: microtubules, motors and MAPs.
|
| Glotzer M.
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| Nat Rev Mol Cell Biol 10(1):9-20. Review. 2009
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| 44 | CDC25C, CDK1, MKLP2, MYT1, PLK1, PLK2, PLK3, PLK4, PPA2, PRC1, SGOL1, WEE1
|
| Polo-like kinases: conservation and divergence in their functions and regulation.
|
| Archambault V, Glover DM.
|
| Nat Rev Mol Cell Biol 10(4):265-75. Review. Erratum in: Nat Rev Mol Cell Biol. 2009 May;10(5):364. 2009
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| 45 | CDK1, CDK5RAP3, CHEK1
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| Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation.
|
| Jiang H, Wu J, He C, Yang W, Li H.
|
| Cell Res 19(4):458-68. 2009
|
| 46 | CDK1, CHEK1
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| Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
|
| Enomoto M, Goto H, Tomono Y, Kasahara K, Tsujimura K, Kiyono T, Inagaki M.
|
| J Biol Chem 284(49):34223-30. Epub 2009 Oct 16.PMID: 19837665 2009
|
| 47 | CDK1
|
| Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration.
|
| Garnier D, Loyer P, Ribault C, Guguen-Guillouzo C, Corlu A.
|
| Hepatology 50(6):1946-56.PMID: 19821535 2009
|
| 48 | CDK1, NEDD1, PLK1, TUBG1
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| Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome.
|
| Zhang X, Chen Q, Feng J, Hou J, Yang F, Liu J, Jiang Q, Zhang C.
|
| J Cell Sci 122(Pt 13):2240-51. Epub 2009 Jun 9.
2009
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| 49 | CDK1, RALBP1
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| Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.
|
| Singhal SS, Yadav S, Vatsyayan R, Chaudhary P, Borvak J, Singhal J, Awasthi S.
|
| Cancer Lett 283(2):152-8. Epub 2009 Apr 17.
2009
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| 50 | CDK1, FOXO1
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| Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons.
|
| Yuan Z, Becker EB, Merlo P, Yamada T, DiBacco S, Konishi Y, Schaefer EM, Bonni A.
|
| Science 319(5870):1665-8. 2008
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| 51 | CDK1, ELAVL1
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| Nuclear HuR accumulation through phosphorylation by Cdk1.
|
| Kim HH, Abdelmohsen K, Lal A, Pullmann R Jr, Yang X, Galban S, Srikantan S, Martindale JL, Blethrow J, Shokat KM, Gorospe M.
|
| Genes Dev 22(13):1804-15.PMID: 18593881 2008
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| 52 | CCNA1, CDK1, CDK2
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| Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events.
|
| De Boer L, Oakes V, Beamish H, Giles N, Stevens F, Somodevilla-Torres M, Desouza C, Gabrielli B.
|
| Oncogene 27(31):4261-8. Epub 2008 Mar 31.
2008
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| 53 | CDK1, EEF2, EEF2K
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| cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.
|
| Smith EM, Proud CG.
|
| EMBO J 27(7):1005-16. doi: 10.1038/emboj.2008.39. Epub 2008 Mar 13.
2008
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| 54 | CDK1, SIRT2
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| Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.
|
| North BJ, Verdin E.
|
| J Biol Chem 282(27):19546-55. Epub 2007 May 8. 2007
|
| 55 | CDK1
|
| Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.
|
| Goga A, Yang D, Tward AD, Morgan DO, Bishop JM.
|
| Nat Med 13(7):820-7. Epub 2007 Jun 24. 2007
|
| 56 | CDK1
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| Cdk1 is sufficient to drive the mammalian cell cycle.
|
| Santamar’a D, BarriŹre C, Cerqueira A, Hunt S, Tardy C, Newton K, C‡ceres JF, Dubus P, Malumbres M, Barbacid M.
|
| Nature 448(7155):811-5. 2007
|
| 57 | CDK1
|
| Mutual inhibition of separase and Cdk1 by two-step complex formation.
|
| Gorr IH, Boos D, Stemmann O.
|
| Mol Cell. 19(1):135-41. 2005
|
| 58 | CDK1, PDKMYT1, WEE1
|
| Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.
|
| Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, Tokumara S, Yahata Y, Tohyama M, Hashimoto K.
|
| J Invest Dermatol 122(6):1356-64.PMID: 15175024 2004
|
| 59 | CDK1
|
| Cell cycle-dependent phosphorylation of Disabled-2 by cdc2.
|
| He J, Xu J, Xu XX, Hall RA.
|
| Oncogene. 22(29):4524-30. 2003
|
| 60 | CDK1, MYT1, MYT1L
|
| Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G(2) delay, revealing a potential checkpoint in early mitosis.
|
| Fletcher L, Cheng Y, Muschel RJ.
|
| Cancer Res 62(1):241-50. 2002
|
| 61 | CDK1, RGC32
|
| RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase.
|
| Badea T, Niculescu F, Soane L, Fosbrink M, Sorana H, Rus V, Shin ML, RusH.
|
| J Biol Chem 277(1):502-8. Epub 2001 Oct 30. 2002
|
| 62 | CDK1
|
| WARTS tumor suppressor is phosphorylated by Cdc2/cyclin B at spindle poles during mitosis.
|
| Morisaki T, Hirota T, Iida S, Marumoto T, Hara T, Nishiyama Y, Kawasuzi M, Hiraoka T, Mimori T, Araki N, Izawa I, Inagaki M, Saya H.
|
| FEBS Lett. 529(2-3):319-24. 2002
|
| 63 | CDK1
|
| GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress.
|
| Vairapandi M, Balliet AG, Hoffman B, Liebermann DA.
|
| J Cell Physiol. 192(3):327-38. 2002
|
| 64 | CDK1, TSC1, TSC2
|
| Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.
|
| Catania MG, Mischel PS, Vinters HV.
|
| J Neuropathol Exp Neurol. 60(7):711-23. 2001
|
| 65 | CDK1
|
| FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis.
|
| Ishii H, Vecchione A, Murakumo Y, Baldassarre G, Numata S, Trapasso F, Alder H, Baffa R, Croce CM.
|
| Proc Natl Acad Sci U S A. 98(18):10374-9. 2001
|
| 66 | CDK1, NES
|
| Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase.
|
| Sahlgren CM, Mikhailov A, Hellman J, Chou YH, Lendahl U, Goldman RD, Eriksson JE.
|
| J Biol Chem. 276(19):16456-63. 2001
|
| 67 | CDK1
|
| Downregulation of the cdc2/cyclin B protein kinase activity by binding of p53 to p34(cdc2).
|
| Ababneh M, Götz C, Montenarh M.
|
| Biochem Biophys Res Commun. 283(2):507-12. 2001
|
| 68 | CDK1
|
| Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.
|
| O'Connor DS, Grossman D, Plescia J, Li F, Zhang H, Villa A, Tognin S, Marchisio PC, Altieri DC.
|
| Proc Natl Acad Sci U S A. 97(24):13103-7. 2000
|
| 69 | ALB, CAD, CCNA2, CDC25A, CDK1, CEBPA, COL1A1, COL1A2, COL3A1, COL6A3, DHFR, DMTF1, GADD45A, JUN, LDHA, MXI1, MYC, ODC1, RCC1, SERPINE1, TERT, TK1, TK2, TP53
|
| c-Myc target genes involved in cell growth, apoptosis, and metabolism.
|
| Dang CV.
|
| Mol Cell Biol 19(1):1-11. Review. No abstract available 1999
|
| 70 | CDK1, LATS2
|
| Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity.
|
| Tao W, Zhang S, Turenchalk GS, Stewart RA, St John MA, Chen W, Xu T.
|
| Nat Genet 21(2):177-81 1999
|
| 71 | CCNB2, CDK1
|
| Functional association of TGF-beta receptor II with cyclin B.
|
| Liu JH, Wei S, Burnette PK, Gamero AM, Hutton M, Djeu JY.
|
| Oncogene 18(1):269-75. 1999
|
| 72 | CDK1, PIN1
|
| The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression.
|
| Wells NJ, Watanabe N, Tokusumi T, Jiang W, Verdecia MA, Hunter T.
|
| J Cell Sci. 112 ( Pt 19):3361-71 1999
|
| 73 | CDK1
|
| Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45.
|
| Zhan Q, Antinore MJ, Wang XW, Carrier F, Smith ML, Harris CC, Fornace AJ Jr.
|
| Oncogene. 18(18):2892-900. 1999
|
| 74 | CDK1
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| The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.
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| 75 | CDK1
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| Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis.
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| 76 | CDC25C, CDK1, CHEK1
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| Science 277 : 1497-1501. 1997
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| 77 | CDK1, PKMYT1
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| The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex.
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| Liu F, Stanton JJ, Wu Z, Piwnica-Worms H.
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| Mol Cell Biol 17(2):571-83. 1997
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| 78 | CDK1
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| MAP4 is the in vivo substrate for CDC2 kinase in HeLa cells: identification of an M-phase specific and a cell cycle-independent phosphorylation site in MAP4.
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| Biochemistry. 36(50):15873-83. 1997
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| 79 | CDK1
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| The Fanconi anemia polypeptide, FAC, binds to the cyclin-dependent kinase, cdc2.
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| 80 | CDK1
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| Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity.
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| 81 | CDK1
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| The protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2.
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| 82 | CDK1
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| A distinct cyclin A is expressed in germ cells in the mouse.
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| 83 | CDK1, KIF11
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| Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo.
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| 84 | CDK1, CDK2
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| KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases.
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| 85 | CDK1
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| Association of proliferating cell nuclear antigen with cyclin-dependent kinases and cyclins in normal and transformed human T lymphocytes.
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| 86 | CDK1
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| Casein kinase II phosphorylates p34cdc2 kinase in G1 phase of the HeLa cell division cycle.
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| 87 | CDK1
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| Regional assignment of the human cell cycle control gene CDC2 to chromosome 10q21 by in situ hybridization.
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| Nazarenko SA, et al.
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| Hum Genet 87 : 621-622. 1991
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| 88 | CDK1
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| A PvuII RFLP detected by pOB231 at CDC2 on human chromosome 10.
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| Carson NL, et al.
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| Nucleic Acids Res 19 : 196. 1991
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| 89 | CDK1
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| Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate.
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| Nature 336(6201):738-44. 1988
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| 90 | CDK1
|
| Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10.
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| Spurr NK, et al.
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| Hum Genet 78 : 333-337. 1988
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| 91 | CDK1
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| Assignment of the human homologue of the yeast cell cycle control gene CDC2 to chromosome 10.
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| Spurr NK, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 698. 1987
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| 92 | CDK1
|
| Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2.
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| Lee MG, et al.
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| Nature 327 : 31-35. 1987
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