Citations for
1CDK1, DDX21, WDR5
DDX21 Interacts with WDR5 to Promote Colorectal Cancer Cell Proliferation by Activating CDK1 Expression.
Lu P, Yu Z, Wang K, Zhai Y, Chen B, Liu M, Xu P, Li F, Zhao Q.
J Cancer. Feb 28;13(5):1530-1539. doi: 10.7150/jca.69216. 2022
2CDK1, DEPDC1B
Overexpressed DEPDC1B contributes to the progression of hepatocellular carcinoma by CDK1
Dang XW, Pan Q, Lin ZH, Wang HH, Li LH, Li L, Shen DQ, Wang PJ.
Aging (Albany NY). May 25;13(16):20094-20115. doi: 10.18632/aging.203016. Epub 2021 May 25. 2021
3CDK1, NFATC1
Inhibition of osteoclasts differentiation by CDC2-induced NFATc1 phosphorylation.
Kim HM, He L, Lee S, Park C, Kim DH, Han HJ, Han J, Hwang J, Cha-Molstad H, Lee KH, Ko SK, Jang JH, Ryoo IJ, Blenis J, Lee HG, Ahn JS, Kwon YT, Soung NK, Kim BY.
Bone. Feb;131:115153. doi: 10.1016/j.bone.2019.115153. Epub 2019 Nov 12 2020
4CCNA1, CDK1, PLK1, PPP1R12A
Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.
Dumitru AMG, Rusin SF, Clark AEM, Kettenbach AN, Compton DA.
Elife 6. pii: e29303. doi: 10.7554/eLife.29303. 2017
5CDK1, VGLL4
Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity
Zeng Y, Stauffer S, Zhou J, Chen X, Chen Y, Dong J.
J Biol Chem. Sep 8;292(36):15028-15038. doi: 10.1074/jbc.M117.796284. Epub 2017 Jul 24. 2017
6CDK1, DES
Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.
Makihara H, Inaba H, Enomoto A, Tanaka H, Tomono Y, Ushida K, Goto M, Kurita K, Nishida Y, Kasahara K, Goto H, Inagaki M.
Biochem Biophys Res Commun 478(3):1323-9. doi: 10.1016/j.bbrc.2016.08.122. Epub 2016 Aug 23. 2016
7CDK1, DNA2, EXO1, WRN
CDK1 phosphorylates WRN at collapsed replication forks.
Palermo V, Rinalducci S, Sanchez M, Grillini F, Sommers JA, Brosh RM Jr, Zolla L, Franchitto A, Pichierri P.
Nat Commun 7:12880. doi: 10.1038/ncomms12880. 2016
8CDK1, PTPRF
LAR protein tyrosine phosphatase regulates focal adhesions through CDK1 .2016 . PMID:
Sarhan AR, Patel TR, Cowell AR, Tomlinson MG, Hellberg C, Heath JK, Cunningham DL, Hotchin NA.
J Cell Sci. Aug 1;129(15):2962-71. doi: 10.1242/jcs.191379. Epub 2016 Jun 27 2016
9CDK1, PLK1, TP53
Polo-like kinase 1 inhibits DNA damage response during mitosis.
Benada J, Burdová K, Lidak T, von Morgen P, Macurek L.
Cell Cycle 14(2):219-31. doi: 10.4161/15384101.2014.977067. 2015
10CDK1, NSUN2
NSun2 Promotes Cell Growth via Elevating Cyclin-Dependent Kinase 1 Translation.
Xing J, Yi J, Cai X, Tang H, Liu Z, Zhang X, Martindale JL, Yang X, Jiang B, Gorospe M, Wang W.
Mol Cell Biol 35(23):4043-52. doi: 10.1128/MCB.00742-15. Epub 2015 Sep 21. 2015
11CDK1, CDKN3
The tumor suppressor CDKN3 controls mitosis.
Nalepa G, Barnholtz-Sloan J, Enzor R, Dey D, He Y, Gehlhausen JR, Lehmann AS, Park SJ, Yang Y, Yang X, Chen S, Guan X, Chen Y, Renbarger J, Yang FC, Parada LF, Clapp W.
J Cell Biol 201(7):997-1012. doi: 10.1083/jcb.201205125. Epub 2013 Jun 17. Erratum in: J Cell Biol. 2013 Aug 19;202(4):717. 2013
12CDK1, MYT1, WEE1
The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.
Chow JP, Poon RY.
Oncogene 32(40):4778-88. doi: 10.1038/onc.2012.504. Epub 2012 Nov 12. 2013
13CDK1, PIN1, PLK1, SEPTIN9
Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis.
Estey MP, Di Ciano-Oliveira C, Froese CD, Fung KY, Steels JD, Litchfield DW, Trimble WS.
J Biol Chem 288(42):30075-86. doi: 10.1074/jbc.M113.474932. Epub 2013 Aug 29. 2013
14CDK1, CDK4, CDK5, UCHL1
Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity.
Kabuta T, Mitsui T, Takahashi M, Fujiwara Y, Kabuta C, Konya C, Tsuchiya Y, Hatanaka Y, Uchida K, Hohjoh H, Wada K.
J Biol Chem 288(18):12615-26. doi: 10.1074/jbc.M112.435701. Epub 2013 Mar 29. 2013
15CDK1, PBK
In silico structural and functional analysis of the human TOPK protein by structure modeling and molecular dynamics studies.
Kirubakaran P, Karthikeyan M, Singh KhD, Nagamani S, Premkumar K.
J Mol Model 19(1):407-19. doi: 10.1007/s00894-012-1566-1. Epub 2012 Sep 1. 2013
16AURKB, CDCA5, CDK1, WAPL
Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.
Nishiyama T, Sykora MM, Huis in 't Veld PJ, Mechtler K, Peters JM.
Proc Natl Acad Sci U S A 110(33):13404-9. doi: 10.1073/pnas.1305020110. Epub 2013 Jul 30. 2013
17CDK1
Increased CDK1 activity determines the timing of kinetochore-microtubule attachments in meiosis I
Davydenko O, Schultz RM, Lampson MA.
J Cell Biol. Jul 22;202(2):221-9. doi: 10.1083/jcb.201303019. Epub 2013 Jul 15. 2013
18CDK1, POU5F1
Cdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectoderm.
Li L, Wang J, Hou J, Wu Z, Zhuang Y, Lu M, Zhang Y, Zhou X, Li Z, Xiao W, Zhang W.
FEBS Lett 586(23):4100-7. doi: 10.1016/j.febslet.2012.10.030. Epub 2012 Oct 26. 2012
19CCNA2, CDK1, CDK2
Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.
Diril MK, Ratnacaram CK, Padmakumar VC, Du T, Wasser M, Coppola V, Tessarollo L, Kaldis P.
Proc Natl Acad Sci U S A 109(10):3826-31. doi: 10.1073/pnas.1115201109. Epub 2012 Feb 21. 2012
20CDK1, CLASP2, PLK1
Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments.
Maia AR, Garcia Z, Kabeche L, Barisic M, Maffini S, Macedo-Ribeiro S, Cheeseman IM, Compton DA, Kaverina I, Maiato H.
J Cell Biol 199(2):285-301. doi: 10.1083/jcb.201203091. Epub 2012 Oct 8. 2012
21CDK1, NEK6, NEK7, NUP98
Phosphorylation of Nup98 by multiple kinases is crucial for NPC disassembly during mitotic entry.
Laurell E, Beck K, Krupina K, Theerthagiri G, Bodenmiller B, Horvath P, Aebersold R, Antonin W, Kutay U.
Cell 144(4):539-50. 2011
22CDK1, CEP250, KIF11
Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.
Smith E, Hégarat N, Vesely C, Roseboom I, Larch C, Streicher H, Straatman K, Flynn H, Skehel M, Hirota T, Kuriyama R, Hochegger H.
EMBO J 30(11):2233-45. Epub 2011 Apr 26. 2011
23CDK1, CEP63
Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance.
Löffler H, Fechter A, Matuszewska M, Saffrich R, Mistrik M, Marhold J, Hornung C, Westermann F, Bartek J, Krämer A.
Cancer Res 71(6):2129-39. 2011
24CDK1, CDK2, CDK5, DNMT1
Phosphorylation of human DNMT1: implication of cyclin-dependent kinases.
Lavoie G, St-Pierre Y.
Biochem Biophys Res Commun 409(2):187-92. Epub 2011 May 1. 2011
25CDK1
Dynamics of Cdk1 substrate specificity during the cell cycle.
Kõivomägi M, Valk E, Venta R, Iofik A, Lepiku M, Morgan DO, Loog M.
Mol Cell 42(5):610-23. 2011
26AURKB, CDK1
Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics.
Nakajima Y, Cormier A, Tyers RG, Pigula A, Peng Y, Drubin DG, Barnes G.
J Cell Biol 194(1):137-53. Epub 2011 Jul 4. 2011
27CDK1, RAD51, RBBP8
Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.
Peterson SE, Li Y, Chait BT, Gottesman ME, Baer R, Gautier J.
J Cell Biol 194(5):705-20. 2011
28BCL2L11, CCNB1, CDK1
Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis.
Mac Fhearraigh S, Mc Gee MM.
Cell Cycle 10(22):3886-96. Epub 2011 Nov 15. 2011
29CDK1, NCAPD3
The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II.
Abe S, Nagasaka K, Hirayama Y, Kozuka-Hata H, Oyama M, Aoyagi Y, Obuse C, Hirota T.
Genes Dev 25(8):863-74. doi: 10.1101/gad.2016411. 2011
30CCNB1, CDK1
Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity.
Matthess Y, Raab M, Sanhaji M, Lavrik IN, Strebhardt K.
Mol Cell Biol ol Cell Biol. 2010 Oct 11. [Epub ahead of print]PMID: 20937773 2010
31CDK1, CDK2, EZH2
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2.
Chen S, Bohrer LR, Rai AN, Pan Y, Gan L, Zhou X, Bagchi A, Simon JA, Huang H.
Nat Cell Biol 2010 Oct 10. [Epub ahead of print]PMID: 20935635 2010
32CDK1, CDK2
Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase.
Maeshima K, Iino H, Hihara S, Funakoshi T, Watanabe A, Nishimura M, Nakatomi R, Yahata K, Imamoto F, Hashikawa T, Yokota H, Imamoto N.
Nat Struct Mol Biol 17(9):1065-71. Epub 2010 Aug 15.PMID: 20711190 2010
33AURKA, CDK1, PLK1
Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
Van Horn RD, Chu S, Fan L, Yin T, Du J, Beckmann R, Mader M, Zhu G, Toth J, Blanchard K, Ye XS.
J Biol Chem 285(28):21849-57. Epub 2010 May 5.PMID: 20444701 2010
34CCNB1, CDK1
Activation of cyclin B1-Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis.
Gavet O, Pines J.
J Cell Biol 189(2):247-59.PMID: 20404109 2010
35CDK1, ZSWIN7
Srs2 plays a critical role in reversible G2 arrest upon chronic and low doses of UV irradiation via two distinct homologous recombination-dependent mechanisms in postreplication repair-deficient cells.
Hishida T, Hirade Y, Haruta N, Kubota Y, Iwasaki H.
Mol Cell Biol 30(20):4840-50. Epub 2010 Aug 16. 2010
36CCNB1, CDK1
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis.
Gavet O, Pines J.
Dev Cell 18(4):533-43. 2010
37CDK1, KMT2E
Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry.
Liu J, Wang XN, Cheng F, Liou YC, Deng LW.
J Biol Chem 285(27):20904-14. doi: 10.1074/jbc.M109.098558. Epub 2010 May 3. 2010
38CDK1, MYT1
A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry.
Ruiz EJ, Vilar M, Nebreda AR.
Curr Biol 20(8):717-23. doi: 10.1016/j.cub.2010.02.050. Epub 2010 Apr 1. 2010
39CDK1
The 3Ms of central spindle assembly: microtubules, motors and MAPs.
Glotzer M.
Nat Rev Mol Cell Biol 10(1):9-20. Review. 2009
40CDC25C, CDK1, MKLP2, MYT1, PLK1, PLK2, PLK3, PLK4, PPA2, PRC1, SGOL1, WEE1
Polo-like kinases: conservation and divergence in their functions and regulation.
Archambault V, Glover DM.
Nat Rev Mol Cell Biol 10(4):265-75. Review. Erratum in: Nat Rev Mol Cell Biol. 2009 May;10(5):364. 2009
41CDK1, CDK5RAP3, CHEK1
Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation.
Jiang H, Wu J, He C, Yang W, Li H.
Cell Res 19(4):458-68. 2009
42CDK1, CHEK1
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.
Enomoto M, Goto H, Tomono Y, Kasahara K, Tsujimura K, Kiyono T, Inagaki M.
J Biol Chem 284(49):34223-30. Epub 2009 Oct 16.PMID: 19837665 2009
43CDK1
Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration.
Garnier D, Loyer P, Ribault C, Guguen-Guillouzo C, Corlu A.
Hepatology 50(6):1946-56.PMID: 19821535 2009
44CDK1, NEDD1, PLK1, TUBG1
Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome.
Zhang X, Chen Q, Feng J, Hou J, Yang F, Liu J, Jiang Q, Zhang C.
J Cell Sci 122(Pt 13):2240-51. Epub 2009 Jun 9. 2009
45CDK1, RALBP1
Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.
Singhal SS, Yadav S, Vatsyayan R, Chaudhary P, Borvak J, Singhal J, Awasthi S.
Cancer Lett 283(2):152-8. Epub 2009 Apr 17. 2009
46CDK1, FOXO1
Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons.
Yuan Z, Becker EB, Merlo P, Yamada T, DiBacco S, Konishi Y, Schaefer EM, Bonni A.
Science 319(5870):1665-8. 2008
47CDK1, ELAVL1
Nuclear HuR accumulation through phosphorylation by Cdk1.
Kim HH, Abdelmohsen K, Lal A, Pullmann R Jr, Yang X, Galban S, Srikantan S, Martindale JL, Blethrow J, Shokat KM, Gorospe M.
Genes Dev 22(13):1804-15.PMID: 18593881 2008
48CCNA1, CDK1, CDK2
Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events.
De Boer L, Oakes V, Beamish H, Giles N, Stevens F, Somodevilla-Torres M, Desouza C, Gabrielli B.
Oncogene 27(31):4261-8. Epub 2008 Mar 31. 2008
49CDK1, EEF2, EEF2K
cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.
Smith EM, Proud CG.
EMBO J 27(7):1005-16. doi: 10.1038/emboj.2008.39. Epub 2008 Mar 13. 2008
50CDK1, SIRT2
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.
North BJ, Verdin E.
J Biol Chem 282(27):19546-55. Epub 2007 May 8. 2007
51CDK1
Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.
Goga A, Yang D, Tward AD, Morgan DO, Bishop JM.
Nat Med 13(7):820-7. Epub 2007 Jun 24. 2007
52CDK1
Cdk1 is sufficient to drive the mammalian cell cycle.
Santamar’a D, Barrire C, Cerqueira A, Hunt S, Tardy C, Newton K, C‡ceres JF, Dubus P, Malumbres M, Barbacid M.
Nature 448(7155):811-5. 2007
53CDK1
Mutual inhibition of separase and Cdk1 by two-step complex formation.
Gorr IH, Boos D, Stemmann O.
Mol Cell. 19(1):135-41. 2005
54CDK1, PDKMYT1, WEE1
Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.
Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, Tokumara S, Yahata Y, Tohyama M, Hashimoto K.
J Invest Dermatol 122(6):1356-64.PMID: 15175024 2004
55CDK1
Cell cycle-dependent phosphorylation of Disabled-2 by cdc2.
He J, Xu J, Xu XX, Hall RA.
Oncogene. 22(29):4524-30. 2003
56CDK1, MYT1, MYT1L
Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G(2) delay, revealing a potential checkpoint in early mitosis.
Fletcher L, Cheng Y, Muschel RJ.
Cancer Res 62(1):241-50. 2002
57CDK1, RGC32
RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase.
Badea T, Niculescu F, Soane L, Fosbrink M, Sorana H, Rus V, Shin ML, RusH.
J Biol Chem 277(1):502-8. Epub 2001 Oct 30. 2002
58CDK1
WARTS tumor suppressor is phosphorylated by Cdc2/cyclin B at spindle poles during mitosis.
Morisaki T, Hirota T, Iida S, Marumoto T, Hara T, Nishiyama Y, Kawasuzi M, Hiraoka T, Mimori T, Araki N, Izawa I, Inagaki M, Saya H.
FEBS Lett. 529(2-3):319-24. 2002
59CDK1
GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress.
Vairapandi M, Balliet AG, Hoffman B, Liebermann DA.
J Cell Physiol. 192(3):327-38. 2002
60CDK1, TSC1, TSC2
Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.
Catania MG, Mischel PS, Vinters HV.
J Neuropathol Exp Neurol. 60(7):711-23. 2001
61CDK1
FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis.
Ishii H, Vecchione A, Murakumo Y, Baldassarre G, Numata S, Trapasso F, Alder H, Baffa R, Croce CM.
Proc Natl Acad Sci U S A. 98(18):10374-9. 2001
62CDK1, NES
Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase.
Sahlgren CM, Mikhailov A, Hellman J, Chou YH, Lendahl U, Goldman RD, Eriksson JE.
J Biol Chem. 276(19):16456-63. 2001
63CDK1
Downregulation of the cdc2/cyclin B protein kinase activity by binding of p53 to p34(cdc2).
Ababneh M, Götz C, Montenarh M.
Biochem Biophys Res Commun. 283(2):507-12. 2001
64CDK1
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.
O'Connor DS, Grossman D, Plescia J, Li F, Zhang H, Villa A, Tognin S, Marchisio PC, Altieri DC.
Proc Natl Acad Sci U S A. 97(24):13103-7. 2000
65ALB, CAD, CCNA2, CDC25A, CDK1, CEBPA, COL1A1, COL1A2, COL3A1, COL6A3, DHFR, DMTF1, GADD45A, JUN, LDHA, MXI1, MYC, ODC1, RCC1, SERPINE1, TERT, TK1, TK2, TP53
c-Myc target genes involved in cell growth, apoptosis, and metabolism.
Dang CV.
Mol Cell Biol 19(1):1-11. Review. No abstract available 1999
66CDK1, LATS2
Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity.
Tao W, Zhang S, Turenchalk GS, Stewart RA, St John MA, Chen W, Xu T.
Nat Genet 21(2):177-81 1999
67CCNB2, CDK1
Functional association of TGF-beta receptor II with cyclin B.
Liu JH, Wei S, Burnette PK, Gamero AM, Hutton M, Djeu JY.
Oncogene 18(1):269-75. 1999
68CDK1, PIN1
The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression.
Wells NJ, Watanabe N, Tokusumi T, Jiang W, Verdecia MA, Hunter T.
J Cell Sci. 112 ( Pt 19):3361-71 1999
69CDK1
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45.
Zhan Q, Antinore MJ, Wang XW, Carrier F, Smith ML, Harris CC, Fornace AJ Jr.
Oncogene. 18(18):2892-900. 1999
70CDK1
The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.
Ball HJ, Melnick A, Shaknovich R, Kohanski RA, Licht JD.
Nucleic Acids Res. 27(20):4106-13. 1999
71CDK1
Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis.
Lowe M, et al.
Cell 94 : 783-793. 1998
72CDC25C, CDK1, CHEK1
Conservation of the Chk1 checkpoint pathway in mammals : linkage of DNA damage to Cdk regulation through Cdc25.
Sanchez Y, et al.
Science 277 : 1497-1501. 1997
73CDK1, PKMYT1
The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex.
Liu F, Stanton JJ, Wu Z, Piwnica-Worms H.
Mol Cell Biol 17(2):571-83. 1997
74CDK1
MAP4 is the in vivo substrate for CDC2 kinase in HeLa cells: identification of an M-phase specific and a cell cycle-independent phosphorylation site in MAP4.
Ookata K, Hisanaga S, Sugita M, Okuyama A, Murofushi H, Kitazawa H, Chari S, Bulinski JC, Kishimoto T.
Biochemistry. 36(50):15873-83. 1997
75CDK1
The Fanconi anemia polypeptide, FAC, binds to the cyclin-dependent kinase, cdc2.
Kupfer GM, Yamashita T, Naf D, Suliman A, Asano S, D'Andrea AD.
Blood. 90(3):1047-54. 1997
76CDK1
Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity.
Booher RN, Holman PS, Fattaey A.
J Biol Chem. 272(35):22300-6. 1997
77CDK1
The protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2.
Pathan NI, Geahlen RL, Harrison ML.
J Biol Chem. 271(44):27517-23. 1996
78CDK1
A distinct cyclin A is expressed in germ cells in the mouse.
Sweeney C, Murphy M, Kubelka M, Ravnik SE, Hawkins CF, Wolgemuth DJ, Carrington M.
Development. 122(1):53-64. 1996
79CDK1, KIF11
Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo.
Blangy A, Lane HA, d'Herin P, Harper M, Kress M, Nigg EA.
Cell 83(7):1159-69. 1995
80CDK1, CDK2
KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases.
Hannon GJ, Casso D, Beach D.
Proc Natl Acad Sci U S A. 91(5):1731-5. 1994
81CDK1
Association of proliferating cell nuclear antigen with cyclin-dependent kinases and cyclins in normal and transformed human T lymphocytes.
Szepesi A, Gelfand EW, Lucas JJ.
Blood. 84(10):3413-21. 1994
82CDK1
Casein kinase II phosphorylates p34cdc2 kinase in G1 phase of the HeLa cell division cycle.
Russo GL, Vandenberg MT, Yu IJ, Bae YS, Franza BR Jr, Marshak DR.
J Biol Chem. 267(28):20317-25. 1992
83CDK1
Regional assignment of the human cell cycle control gene CDC2 to chromosome 10q21 by in situ hybridization.
Nazarenko SA, et al.
Hum Genet 87 : 621-622. 1991
84CDK1
A PvuII RFLP detected by pOB231 at CDC2 on human chromosome 10.
Carson NL, et al.
Nucleic Acids Res 19 : 196. 1991
85CDK1
Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate.
Draetta G, Piwnica-Worms H, Morrison D, Druker B, Roberts T, Beach D.
Nature 336(6201):738-44. 1988
86CDK1
Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10.
Spurr NK, et al.
Hum Genet 78 : 333-337. 1988
87CDK1
Assignment of the human homologue of the yeast cell cycle control gene CDC2 to chromosome 10.
Spurr NK, et al.
(HGM9) Cytogenet Cell Genet 46 : 698. 1987
88CDK1
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2.
Lee MG, et al.
Nature 327 : 31-35. 1987