Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

HK1

contributors: mct/npt - updated : 22-12-2020

HGNC name	hexokinase 1
HGNC id	4922

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

HK1 , HMSNR , RP79 , NEDVIBA

related resource

MITOP database

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   reduced erythroid transcription of HK1 together with aberrant splicing of both HK1 and red cell specific-hexokinase results in hexokinase deficiency and mild chronic hemolysis (de Vooght 2009)

Susceptibility

to variation of glycated hemoglobin levels in a non-diabetic population

Variant & Polymorphism other	association between glycated hemoglobin levels and HK1 polymorphisms (Pare 2008)

Candidate gene
Marker	overexpression of HK1 may act as a significant biomarker of poor prognosis for patients with colorectal cancer
Therapy target

ANIMAL & CELL MODELS