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FLASH GENE
Symbol GPR78 contributors: mct - updated : 18-05-2009
HGNC name G protein-coupled receptor 78
HGNC id 4528
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane domain
    • HOMOLOGY
    intraspecies homolog to GPR26
    Homologene
    FAMILY
  • G-protein coupled receptor 1 family
    • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • transducing extracellular signals through heterotrimeric G protein
  • activate G proteins in a manner that is distinct from other group 1 GPCRs
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to bipolar affective disorder and schizophrenia (BPAD and SCZ) in the Scottish population
    Variant & Polymorphism SNP increasing the risk of bipolar affective disorder and schizophrenia in females
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS