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FLASH GENE
Symbol GPR78 contributors: mct - updated : 18-05-2009
HGNC name G protein-coupled receptor 78
HGNC id 4528
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain     Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text in developing brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane domain
    • HOMOLOGY
    intraspecies homolog to GPR26
    Homologene
    FAMILY
  • G-protein coupled receptor 1 family
    • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • transducing extracellular signals through heterotrimeric G protein
  • activate G proteins in a manner that is distinct from other group 1 GPCRs
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to bipolar affective disorder and schizophrenia (BPAD and SCZ) in the Scottish population
    Variant & Polymorphism SNP increasing the risk of bipolar affective disorder and schizophrenia in females
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS