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FLASH GENE
Symbol PARVG contributors: - updated : 19-03-2005
HGNC name parvin, gamma
HGNC id 14654
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
two calponin-homology (CM) domains
HOMOLOGY
interspecies ortholog to murine Parvg
ortholog to Drosophila Cg12533
ortholog to C.elegans Pat-6
intraspecies paralog to PARVA
paralog to PARVB
Homologene
FAMILY parvin family of focal adhesion proteins
CATEGORY adhesion
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
text located to focal adhesions
basic FUNCTION
  • playing a role in the regulation of cell adhesion and cytoskeleton organsation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding to ILK and actin
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS