Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|
|
| --low
|
|
in mammary carcinoma by hypermethylation and invulval squamous neoplasia |
tumoral
|
|
| --low
|
|
in prostate cancer |
tumoral
|
|
| --low
|
|
involved in the uncontrolled cell cycle in intrahepatic cholangiocarcinoma and is a significant indicator of poor prognosis for patients with intrahepatic cholangiocarcinoma  |
tumoral
|
|
| --over
|
|
in gastric cancer, significantly correlated with clinical stage and tumor invasion  |
tumoral
|
|
| --over
|
|
hypomethylation of the promoter leads to increased expression in non-small cell lung cancer  |
tumoral
|
|
|
|
|
epigenetic silencing of 14-3-3sigma might contribute to tumor progression in malignant melanoma via loss of cell cycle control, impaired cellular senescence program  |
tumoral
|
|
| --over
|
|
aberrant overexpression of SFN (stratifin) plays an oncogenic role in lung adenocarcinoma  |
tumoral
|
|
| --over
|
|
in ovarian cancers is significantly correlated with worse postprogression survival  |