| 1 | LRFN4, NCK1, SFN
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| A neuronal transmembrane protein LRFN4 complexes with 14-3-3s and NCK1 to induce morphological change in monocytic cells via Rac1-mediated actin cytoskeleton reorganization.
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| Konakahara S, Suzuki Y, Kawakami T, Saitou M, Kajikawa M, Masuho Y, Kohroki J.
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| FEBS Lett EBS Lett. 2012 Jun 4. [Epub ahead of print]
2012
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| 2 | SFN
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| Aberrant upregulation of 14-3-3ơ expression serves as an inferior prognostic biomarker for gastric cancer.
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| Zhou WH, Tang F, Xu J, Wu X, Feng ZY, Li HG, Lin DJ, Shao CK, Liu Q.
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| BMC Cancer 11:397.
2011
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| 3 | SFN, TP63
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| 14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
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| Li Q, Sambandam SA, Lu HJ, Thomson A, Kim SH, Lu H, Xin Y, Lu Q.
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| Carcinogenesis 32(12):1782-8. Epub 2011 Sep 16.
2011
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| 4 | SFN
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| Hypomethylation of the 14-3-3σ promoter leads to increased expression in non-small cell lung cancer.
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| Radhakrishnan VM, Jensen TJ, Cui H, Futscher BW, Martinez JD.
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| Genes Chromosomes Cancer 50(10):830-6. doi: 10.1002/gcc.20904. Epub 2011 Jul 13.
2011
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| 5 | COPS6, RFWD2, SFN
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| COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ.
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| Choi HH, Gully C, Su CH, Velazquez-Torres G, Chou PC, Tseng C, Zhao R, Phan L, Shaiken T, Chen J, Yeung SC, Lee MH.
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| Oncogene 30(48):4791-801. doi: 10.1038/onc.2011.192. Epub 2011 May 30.
2011
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| 6 | SFN
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| 14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.
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| Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW.
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| Proc Natl Acad Sci U S A 108(4):1555-60. Epub 2011 Jan 4. Erratum in: Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6689. Hermeking, Heiko [added]; Vogel 2011
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| 7 | SFN
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| 14-3-3sigma controls corneal epithelial cell proliferation and differentiation through the Notch signaling pathway.
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| Xin Y, Lu Q, Li Q.
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| Biochem Biophys Res Commun 392(4):593-8. Epub 2010 Jan 25.PMID: 20100467 2010
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| 8 | SFN
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| A novel role for 14-3-3sigma in regulating epithelial cell polarity.
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| Ling C, Zuo D, Xue B, Muthuswamy S, Muller WJ.
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| Genes Dev 24(9):947-56.PMID: 20439433 2010
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| 9 | RFWD2, SFN
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| Nuclear export regulation of COP1 by 14-3-3 sigma in response to DNA damage.
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| Su CH, Zhao R, Velazquez-Torres G, Chen J, Gully C, Yeung SC, Lee MH.
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| Mol Cancer 9(1):243. [Epub ahead of print]PMID: 20843328 2010
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| 10 | SFN
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| 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.
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| Schultz J, Ibrahim SM, Vera J, Kunz M.
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| Mol Cancer 8:53.
2009
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| 11 | SFN
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| The 14-3-3sigma gene promoter is methylated in both human melanocytes and melanoma.
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| Liu S, Howell P, Ren S, Fodstad O, Riker AI.
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| BMC Cancer 9:162.
2009
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| 12 | CA11, CCAR1, MDM2, SFN
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| CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2.
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| Yang W, Dicker DT, Chen J, El-Deiry WS.
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| Cell Cycle 7(5):670-82. Epub 2008 Jan 31. 2008
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| 13 | SFN
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| 14-3-3sigma negatively regulates the cell cycle, and its down-regulation is associated with poor outcome in intrahepatic cholangiocarcinoma.
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| Kuroda Y, Aishima S, Taketomi A, Nishihara Y, Iguchi T, Taguchi K, Maehara Y, Tsuneyoshi M.
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| Hum Pathol 38(7):1014-22. Epub 2007 Mar 28.
2007
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| 14 | IRF6, SFN
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| Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch.
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| Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ.
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| Nat Genet 38(11):1329-34. Epub 2006 Oct 15. 2006
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| 15 | SFN, CA11
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| 14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decay.
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| He C, Schneider R.
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| EMBO J 25(16):3823-31. Epub 2006 Aug 10. 2006
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| 16 | SFN
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| Identification and distribution of 14.3.3sigma (stratifin) in the human cornea.
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| Zanello SB, Nayak R, Zanello LP, Farthing-Nayak P.
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| Curr Eye Res 31(10):825-33. 2006
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| 17 | SFN
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| 14-3-3sigma is down-regulated in human prostate cancer.
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| Urano T, Takahashi S, Suzuki T, Fujimura T, Fujita M, Kumagai J, Horie-Inoue K, Sasano H, Kitamura T, Ouchi Y, Inoue S.
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| Biochem Biophys Res Commun 319(3):795-800. 2004
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| 18 | SFN, CDKN2A
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| Coincident inactivation of 14-3-3sigma and p16INK4a is an early event in vulval squamous neoplasia.
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| Gasco M, Sullivan A, Repellin C, Brooks L, Farrell PJ, Tidy JA, Dunne B, Gusterson B, Evans DJ, Crook T.
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| Oncogene 21(12):1876-81. 2002
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| 19 | SFN
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| Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.
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| Umbricht CB, Evron E, Gabrielson E, Ferguson A, Marks J, Sukumar S.
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| Oncogene 20(26):3348-53. 2001
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| 20 | SFN
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| Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells.
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| Prasad GL, Valverius EM, McDuffie E, Cooper HL.
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| Cell Growth Differ 3(8):507-13. 1992
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