| 1 | SFN
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| Stratifin promotes the malignant progression of HCC via binding and hyperactivating AKT signaling.
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| Li R, Yan X, Zhong W, Zheng J, Li X, Liang J, Hu Z, Liu H, Chen G, Yang Y, Zhang J, Qu E, Liu W.
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| Cancer Lett. Jun 28;592:216761. doi: 10.1016/j.canlet.2024.216761. Epub 2024 Mar 13. 2024
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| 2 | SFN
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| Stratifin promotes the growth and proliferation of hepatocellular carcinoma.
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| Zhao X, Wang E, Xu H, Zhang L.
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| Tissue Cell. Jun;82:102080. doi: 10.1016/j.tice.2023.102080. Epub 2023 Mar 27 2023
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| 3 | SFN
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| Serum Extracellular Vesicle Stratifin Is a Biomarker of Perineural Invasion in Patients With Colorectal Cancer and Predicts Worse Prognosis.
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| Hou W, Pan M, Xiao Y, Ge W.
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| Front Oncol. Jul 22;12:912584. doi: 10.3389/fonc.2022.912584 2022
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| 4 | SFN
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| Stratifin in ocular surface squamous neoplasia and its association with p53.
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| Chauhan S, Sen S, Chauhan SS, Pushker N, Tandon R, Kashyap S, Vanathi M, Bajaj MS
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| Acta Ophthalmol. Dec;99(8):e1483-e1491. doi: 10.1111/aos.14844. Epub 2021 Mar 26. 2021
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| 5 | SFN
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| Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma.
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| Robin F, Angenard G, Cano L, Courtin-Tanguy L, Gaignard E, Khene ZE, Bergeat D, Clément B, Boudjema K, Coulouarn C, Sulpice L.
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| Br J Cancer. Jul;123(1):72-80. doi: 10.1038/s41416-020-0863-1. Epub 2020 May 7. 2020
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| 6 | GORASP2, SFN, ZYG11A
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| DNA hypomethylation-related overexpression of SFN, GORASP2 and ZYG11A is a novel prognostic biomarker for early stage lung adenocarcinoma.
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| Husni RE, Shiba-Ishii A, Nakagawa T, Dai T, Kim Y, Hong J, Sakashita S, Sakamoto N, Sato Y, Noguchi M.
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| Oncotarget. Feb 26;10(17):1625-1636. doi: 10.18632/oncotarget.26676. 2019
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| 7 | SFN, SKP1
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| Stratifin Inhibits SCFFBW7 Formation and Blocks Ubiquitination of Oncoproteins during the Course of Lung Adenocarcinogenesis.
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| Shiba-Ishii A, Hong J, Hirokawa T, Kim Y, Nakagawa T, Sakashita S, Sakamoto N, Kozuma Y, Sato Y, Noguchi M.
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| Clin Cancer Res. May 1;25(9):2809-2820. doi: 10.1158/1078-0432.CCR-18-3631. Epub 2019 Feb 6. 2019
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| 8 | SFN
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| Expression profile and prognostic value of SFN in human ovarian cancer.
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| Hu Y, Zeng Q, Li C, Xie Y.
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| Biosci Rep. May 2;39(5):BSR20190100. doi: 10.1042/BSR20190100 2019
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| 9 | PKP3, SFN
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| 14-3-3 proteins regulate desmosomal adhesion via plakophilins.
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| Rietscher K, Keil R, Jordan A, Hatzfeld M.
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| J Cell Sci. May 22;131(10):jcs212191. doi: 10.1242/jcs.212191. 2018
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| 10 | SFN
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| Stratifin accelerates progression of lung adenocarcinoma at an early stage
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| Shiba-Ishii A, Kim Y, Shiozawa T, Iyama S, Satomi K, Kano J, Sakashita S, Morishita Y, Noguchi M.
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| Mol Cancer. Jul 30;14:142. doi: 10.1186/s12943-015-0414-1. 2015
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| 11 | PKP3, SFN
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| Stratifin (14-3-3 σ) limits plakophilin-3 exchange with the desmosomal plaque.
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| Roberts BJ, Reddy R, Wahl JK 3rd
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| PLoS One. Oct 4;8(10):e77012. doi: 10.1371/journal.pone.0077012. 2013
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| 12 | LRFN4, NCK1, SFN
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| A neuronal transmembrane protein LRFN4 complexes with 14-3-3s and NCK1 to induce morphological change in monocytic cells via Rac1-mediated actin cytoskeleton reorganization.
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| Konakahara S, Suzuki Y, Kawakami T, Saitou M, Kajikawa M, Masuho Y, Kohroki J.
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| FEBS Lett EBS Lett. 2012 Jun 4. [Epub ahead of print]
2012
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| 13 | SFN
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| Aberrant upregulation of 14-3-3ơ expression serves as an inferior prognostic biomarker for gastric cancer.
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| Zhou WH, Tang F, Xu J, Wu X, Feng ZY, Li HG, Lin DJ, Shao CK, Liu Q.
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| BMC Cancer 11:397.
2011
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| 14 | SFN, TP63
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| 14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
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| Li Q, Sambandam SA, Lu HJ, Thomson A, Kim SH, Lu H, Xin Y, Lu Q.
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| Carcinogenesis 32(12):1782-8. Epub 2011 Sep 16.
2011
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| 15 | SFN
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| Hypomethylation of the 14-3-3σ promoter leads to increased expression in non-small cell lung cancer.
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| Radhakrishnan VM, Jensen TJ, Cui H, Futscher BW, Martinez JD.
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| Genes Chromosomes Cancer 50(10):830-6. doi: 10.1002/gcc.20904. Epub 2011 Jul 13.
2011
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| 16 | COP1, COPS6, SFN
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| COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ.
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| Choi HH, Gully C, Su CH, Velazquez-Torres G, Chou PC, Tseng C, Zhao R, Phan L, Shaiken T, Chen J, Yeung SC, Lee MH.
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| Oncogene 30(48):4791-801. doi: 10.1038/onc.2011.192. Epub 2011 May 30. 2011
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| 17 | SFN
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| 14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.
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| Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW.
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| Proc Natl Acad Sci U S A 108(4):1555-60. Epub 2011 Jan 4. Erratum in: Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6689. Hermeking, Heiko [added]; Vogel 2011
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| 18 | SFN
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| 14-3-3sigma controls corneal epithelial cell proliferation and differentiation through the Notch signaling pathway.
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| Xin Y, Lu Q, Li Q.
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| Biochem Biophys Res Commun 392(4):593-8. Epub 2010 Jan 25.PMID: 20100467 2010
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| 19 | SFN
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| A novel role for 14-3-3sigma in regulating epithelial cell polarity.
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| Ling C, Zuo D, Xue B, Muthuswamy S, Muller WJ.
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| Genes Dev 24(9):947-56.PMID: 20439433 2010
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| 20 | COP1, SFN
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| Nuclear export regulation of COP1 by 14-3-3 sigma in response to DNA damage.
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| Su CH, Zhao R, Velazquez-Torres G, Chen J, Gully C, Yeung SC, Lee MH.
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| Mol Cancer 9(1):243. [Epub ahead of print]PMID: 20843328 2010
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| 21 | SFN
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| 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.
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| Schultz J, Ibrahim SM, Vera J, Kunz M.
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| Mol Cancer 8:53.
2009
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| 22 | SFN
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| The 14-3-3sigma gene promoter is methylated in both human melanocytes and melanoma.
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| Liu S, Howell P, Ren S, Fodstad O, Riker AI.
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| BMC Cancer 9:162.
2009
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| 23 | CA11, CCAR1, MDM2, SFN
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| CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2.
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| Yang W, Dicker DT, Chen J, El-Deiry WS.
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| Cell Cycle 7(5):670-82. Epub 2008 Jan 31. 2008
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| 24 | SFN
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| 14-3-3sigma negatively regulates the cell cycle, and its down-regulation is associated with poor outcome in intrahepatic cholangiocarcinoma.
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| Kuroda Y, Aishima S, Taketomi A, Nishihara Y, Iguchi T, Taguchi K, Maehara Y, Tsuneyoshi M.
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| Hum Pathol 38(7):1014-22. Epub 2007 Mar 28.
2007
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| 25 | IRF6, SFN
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| Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch.
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| Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ.
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| Nat Genet 38(11):1329-34. Epub 2006 Oct 15. 2006
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| 26 | SFN, CA11
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| 14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decay.
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| He C, Schneider R.
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| EMBO J 25(16):3823-31. Epub 2006 Aug 10. 2006
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| 27 | SFN
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| Identification and distribution of 14.3.3sigma (stratifin) in the human cornea.
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| Zanello SB, Nayak R, Zanello LP, Farthing-Nayak P.
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| Curr Eye Res 31(10):825-33. 2006
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| 28 | SFN
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| 14-3-3sigma is down-regulated in human prostate cancer.
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| Urano T, Takahashi S, Suzuki T, Fujimura T, Fujita M, Kumagai J, Horie-Inoue K, Sasano H, Kitamura T, Ouchi Y, Inoue S.
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| Biochem Biophys Res Commun 319(3):795-800. 2004
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| 29 | SFN, CDKN2A
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| Coincident inactivation of 14-3-3sigma and p16INK4a is an early event in vulval squamous neoplasia.
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| Gasco M, Sullivan A, Repellin C, Brooks L, Farrell PJ, Tidy JA, Dunne B, Gusterson B, Evans DJ, Crook T.
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| Oncogene 21(12):1876-81. 2002
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| 30 | SFN
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| Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.
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| Umbricht CB, Evron E, Gabrielson E, Ferguson A, Marks J, Sukumar S.
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| Oncogene 20(26):3348-53. 2001
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| 31 | SFN
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| Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells.
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| Prasad GL, Valverius EM, McDuffie E, Cooper HL.
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| Cell Growth Differ 3(8):507-13. 1992
|