| basic FUNCTION
| playing a central coordinating role for tyrosine-kinase based signaling related to cell-adhesion and induction of cell migration |
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acting as a signal transducer |
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being a key component in the netrin signal transduction pathway |
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playing an important role in guiding commissural axons |
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junction protein that is important to the adhesion between cytoskeleton and extracellular matrix  |
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plays important roles in the invasion, metastasis and prognosis of hepatocellular carcinoma |
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role in the regulation of vascular smooth muscle contractility, cell migration, hypertrophy, and growth |
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act as scaffolds to regulate protein complexes controlling migration and chemotaxis, apoptosis, cell cycle, and differentiation, and is linked to a role in progenitor cell function |
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represents a nodal scaffold protein regulating cell survival, migration, and proliferation in normal and pathological cells |
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essential transducer in ERBB2 transformation |
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important role for Cas proteins in cell-cell adhesion signaling in development |
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new role for CAS proteins in cell-cell adhesion signaling in cancer |
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major tyrosine-phosphorylated protein in cells transformed by CRK and SRC oncogenes, playing an important role in invasiveness of SRC-transformed cells |
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BCAR1 and EZR are structural proteins with an important role in signaling pathways and have been shown to promote cancer dissemination |
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in Ovarian cancer, the role of EZR in disease progression is more pronounced than that of BCAR1 |
