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FLASH GENE
Symbol ADAMTS15 contributors: npt/ - updated : 26-09-2002
HGNC name ADAM metallopeptidase with thrombospondin type 1 motif, 15
HGNC id 16305
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • ADAM cystein-rich domain
  • thrombospondin type 1 domain
    • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to C.elegans R10H10.1
    Homologene
    FAMILY
  • ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family
  • reprolysin family zinc metalloprotease
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in intestinal epithelial cells wound-healing processes and may have important pathophysiological roles in intestinal cells
    • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS