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FLASH GENE
Symbol LAT contributors: mct/npt/pgu - updated : 30-08-2017
HGNC name linker for activation of T cells
HGNC id 18874
ANIMAL & CELL MODELS
  • T cells from mice harboring a mutation at the Plcg1 binding site of Lat (Y136F) have impaired calcium flux and Erk activation, and these T cells are highly activated, resulting in the development of a lymphoproliferative syndrome