System | Type | Disorder | Pubmed |
cancer | reproductive | ovary | |
targeting of its overexpression by immunotherapeutic strategies may represent an attractive and potentially effective approach in patients harbouring epithelial ovarian cancer |
cancer | endocrine | pancreas | |
might be a useful treatment approach for patients with pancreatic cancer overexpressing this cell-surface marker |
cancer | | | |
oncogene that has potential as a therapeutic target, and having a restricted expression in normal tissue, anti-Trop-2 therapeutics would be predicted to have limited toxicity |
cancer | reproductive | prostate | |
is a driver and therapeutic target for metastatic prostate cancer with neuroendocrine phenotype |
cancer | digestive | colon | |
is a target in metastatic colon cancer |
cancer | | | |
potential therapeutic target in human solid tumors |