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FLASH GENE

Symbol

KIF15

contributors: mct - updated : 27-04-2020

HGNC name	kinesin family member 15
HGNC id	17273

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       gain of function in glioma tumor tissues and positively correlated with pathological staging, recurrence risk and poor prognosis tumoral       gain of function in human pancreatic cancer tissues

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	served as a prognostic indicator for glioma
	may serve as a novel diagnostic target for melanoma, especially uveal melanoma
	higher KIF15 expression levels correlated with shorter patient survival times in pancreatic cancer
Therapy target
	System Type Disorder Pubmed cancer brain glioma/neuroblstoma may be a therapeutic target for glioma therapy cancer digestive liver KIF15 could be a novel therapeutic target for the treatment of hepatocellular carcinoma (HCC) cancer eye   therapeutic target for melanoma, especially uveal melanoma

ANIMAL & CELL MODELS