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FLASH GENE
Symbol CHST3 contributors: mct - updated : 05-03-2007
HGNC name carbohydrate (chondroitin 6) sulfotransferase 3
HGNC id 1971
DNA
TYPE functioning gene
STRUCTURE 49.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   highly
Endocrinepancreas    
Lymphoid/Immunethymus   highly
Nervousbrain    
Reproductivemale systemprostate  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
Epithelialsecretoryglandularendocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a transmembrane domain
  • a sulfotransferase domain
    • HOMOLOGY
    interspecies homolog to murine Chst3
    homolog to Drosophila CG1332
    homolog to C.elegans T01H10.8
    Homologene
    FAMILY
  • sulfotransferase family
  • Gal/GlcNAc/GalNAc subfamily
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    text Golgi membrane-bound
    basic FUNCTION catalyzing the sulfation of keratan sulfate
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    mucopolysaccharides
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) SEDO , LRS2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS