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FLASH GENE
Symbol TNXB contributors: mct - updated : 27-09-2011
HGNC name tenascin XB
HGNC id 11976
ASSOCIATED DISORDERS
corresponding disease(s) EDSL1 , VUR8
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in malignant mesothelioma compared with ovarian/peritoneal serous carcinoma
Susceptibility
  • to rheumatoid arthritis
  • to systemic lupus erythematosus
  • Variant & Polymorphism SNP increasing the risk of systemic lupus erythematosus
    Candidate gene
    Marker
  • may be a new diagnostic marker of malignant mesothelioma in the differential diagnosis of cancers involving the serosal cavities, particularly in the differential diagnosis between this tumor and ovarian/peritoneal serous carcinoma
  • Therapy target
    ANIMAL & CELL MODELS