Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol OSBPL7 contributors: mct - updated : 09-02-2013
HGNC name oxysterol binding protein-like 7
HGNC id 16387
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal pleckstrin homology PH domain
  • a highly conserved OSBP-type sterol binding domain in the C terminus
    • HOMOLOGY
    Homologene
    FAMILY oxysterol binding protein family
    CATEGORY receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • may be involved in protein-protein and protein-lipid interactions
  • putative role in communication between the ER and the plasma membrane
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction partner of OSBPL7, GABARAPL2 which regulates Golgi SNARE of 28kDa (GS28) function and stability, and plays a role in autophagosome biogenesis
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS