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FLASH GENE

Symbol

SIRT5

contributors: mct/npt - updated : 29-04-2020

HGNC name	sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
HGNC id	14933

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in human breast tumors correlates with poor patient prognosis

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may serve as a potential prognostic factor for intervention in non-small cell lung cancer
Therapy target
	System Type Disorder Pubmed cancer lung   SIRT5/SUN2 axis may prove to be useful for the development of new strategies for treating the patients with lung cancer cancer digestive liver may function as a novel potential therapeutic target for HCC cancer lung   drug target for intervention in non-small cell lung cancer

ANIMAL & CELL MODELS

Sirt5-deficient mice are resistant to viral infection (