| Symbol
| ATP10A
| contributors: mct - updated : 29-06-2021
|
| HGNC name
| ATPase, Class V, type 10A
|
| HGNC id
| 13542
|
| corresponding disease(s)
|
AS
|
| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| constitutional
|
| deletion
|
|
| |
included in PWS/AS typically deleted region, maternally expressed gene | | constitutional
|
|
| --other
|
| |
dysregulation contributes to some of the obesity-related complications in PWS and in individuals with 15q11-q13 duplication | | constitutional
|
|
| --over
|
|
in Hereditary spastic paraplegias (HSPs) with intellectual disability (ID)  | |
Variant & Polymorphism
| 
| |
Candidate gene
Marker
Therapy target
|
| | | |
|
| deficiency of Atp10a and Atp10d leads to insulin resistance and obesity in mice |