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FLASH GENE
Symbol ATP10A contributors: mct - updated : 29-06-2021
HGNC name ATPase, Class V, type 10A
HGNC id 13542
ASSOCIATED DISORDERS
corresponding disease(s) AS
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional   deletion    
included in PWS/AS typically deleted region, maternally expressed gene
constitutional     --other  
dysregulation contributes to some of the obesity-related complications in PWS and in individuals with 15q11-q13 duplication
constitutional     --over  
in Hereditary spastic paraplegias (HSPs) with intellectual disability (ID)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • deficiency of Atp10a and Atp10d leads to insulin resistance and obesity in mice