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FLASH GENE
Symbol ADD3 contributors: - updated : 31-03-2006
HGNC name adducin 3 (gamma)
HGNC id 245
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal globular protease resistent domain
  • a potential protein kinase C phosphorylation site
  • a calmodulin binding site
  • a C terminus homolog to MARCKS proteins, alternatively spliced
    • mono polymer homomer , heptamer
    HOMOLOGY
    Homologene
    FAMILY aldolase class II family, adducin subfamily
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,nucleus
    basic FUNCTION
  • membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma
    INTERACTION
    DNA
    RNA
    small molecule
    protein calmodulin binding
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS