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FLASH GENE
Symbol CAP1 contributors: mct - updated : 03-05-2017
HGNC name CAP, adenylate cyclase-associated protein 1 (yeast)
HGNC id 20040
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in human glioma
tumoral     --over  
is involved in the pathogenesis of epithelial ovarian cancer (EOC)
tumoral     --over  
might contribute heavily to the metastasis of Hepatocellular carcinoma (HCC)
tumoral     --over  
1 in lung cancer cells, particularly at the metastatic stage, may have significant clinical implications as a diagnostic/prognostic factor for lung cancer
tumoral     --over  
in pancreatic cancers
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • CAP1 could be an independent prognostic factor for patients survival in Hepatocellular carcinoma (HCC)
  • Therapy target
    SystemTypeDisorderPubmed
    cancerbrain 
    downregulation of CAP1 in tumors may serve as a treatment for glioma patients
    cancerreproductiveovary
    downregulation of CAP1 in tumor cells may be a therapeutic target for the treatment of patients with EOC
    ANIMAL & CELL MODELS