| basic FUNCTION
| playing a role in the physiologic control of fluid and electrolyte homeostasis |
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acting in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels |
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potent hypotensive and vasodilatator agent |
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acting as a survival factor in osteoblastic cells via a CALCA receptor-MEK-ERK pathway, which provides further understanding on the physiological function of ADM in osteoblasts  |
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required for the normal development of the lymphatic vascular system and having role in controlling lymphatic endothelial permeability and lymphatic flow through reorganization of junctional proteins |
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stimulates ciliary motility of the human oviduct ( |
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plays an important role in the regulation of osteoblastic cells through both a proliferative and an anti-apoptotic effects |
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could also exert its survival effect in osteoblast via components of the Wnt pathway |
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is indeed a factor that can possibi1ity affect cumulus cells and oocytes and involve meiotic arrest during oocyte maturation |
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regulates the proliferation rate and the differentiation into neurons, astrocytes, and oligodendrocytes of stem/progenitor cells, probably through the PI3K/Akt pathway |
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may contribute to neural stem cell growth regulation by allowing cells to pass through mitosis |
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promotes osteoblast growth and proliferation, inducing an increase in bone mass |
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facilitates voltage-dependent Ca(2+) channels in osteoblasts |
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expression of the pregnancy-related peptide adrenomedullin by fetal trophoblast cells is necessary and sufficient to promote appropriate recruitment and activation of maternal uterine NK (uNK) cells to the placenta and ultimately facilitate remodeling of maternal |
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exerts anti-inflammatory and antibacterial effects and stimulates mucosal regeneration for the maintenance of the colonic epithelial barrier |
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acts as an autocrine and/or paracrine factor to play a key role in the regulation of cardiovascular function |
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can act as a GVBD (germinal vesicle breakdown) regulator |
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major regulators of vascular tone and cardiovascular development |
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ADM-RAMP2 system suppresses ER stress-induced tubule cell death, thereby exerting a protective effect on kidney |
