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FLASH GENE

Symbol

MPO

contributors: mct - updated : 28-11-2017

HGNC name	myeloperoxidase
HGNC id	7218

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Mpo-deficient mice were protected from atrial fibrillation, which was reversed when MPO was restored
	Mpo deficiency upregulates the expression of several proinflammatory cytokines and chemokines in mouse neutrophils
	in diabetic rat aortas, both Mpo expresion and NADPH oxidase activity were increased while the endothelial function was simultaneously impaired