| 1 | MPO, MPOD
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| Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease.
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| Vergnano M, Mockenhaupt M, Benzian-Olsson N, Paulmann M, Grys K, Mahil SK, Chaloner C, Barbosa IA, August S, Burden AD, Choon SE, Cooper H, Navarini AA, Reynolds NJ, Wahie S, Warren RB, Wright A; APRICOT and PLUM study team, Huffmeier U, Baum P, Visvanathan S, Barker JN, Smith CH, Capon F.
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| Am J Hum Genet. Sep 3;107(3):539-543. doi: 10.1016/j.ajhg.2020.06.020. Epub 2020 Aug 5. 2020
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| 2 | MPO
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| Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation.
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| Grishkovskaya I, Paumann-Page M, Tscheliessnig R, Stampler J, Hofbauer S, Soudi M, Sevcnikar B, Oostenbrink C, Furtmüller PG, Djinović-Carugo K, Nauseef WM, Obinger C.
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| J Biol Chem 292(20):8244-8261. doi: 10.1074/jbc.M117.775031. Epub 2017 Mar 27.
2017
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| 3 | MPO, SERPING1
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| Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1).
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| Hair PS, Sass LA, Krishna NK, Cunnion KM.
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| PLoS One 12(1):e0170203. doi: 10.1371/journal.pone.0170203. eCollection 2017.
2017
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| 4 | MPO
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| Myeloperoxidase amplified high glucose-induced endothelial dysfunction in vasculature: Role of NADPH oxidase and hypochlorous acid.
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| Tian R, Ding Y, Peng YY, Lu N.
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| Biochem Biophys Res Commun 484(3):572-578. doi: 10.1016/j.bbrc.2017.01.132. Epub 2017 Jan 26.
2017
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| 5 | MPO
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| Myeloperoxidase in blood neutrophils during normal and abnormal menstrual cycles in women of reproductive age.
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| Shibata T, Sakamoto J, Osaka Y, Neyatani N, Fujita S, Oka Y, Takagi H, Mori H, Fujita H, Tanaka Y, Sasagawa T.
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| Int J Lab Hematol 39(2):169-174. doi: 10.1111/ijlh.12599. Epub 2016 Dec 25.
2017
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| 6 | EPX, MPO, TNFSF11
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| Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.
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| Panagopoulos V, Liapis V, Zinonos I, Hay S, Leach DA, Ingman W, DeNichilo MO, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A.
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| Mol Cell Endocrinol 440:8-15. doi: 10.1016/j.mce.2016.11.007. Epub 2016 Nov 9.
2017
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| 7 | EPX, MPO
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| Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.
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| Panagopoulos V, Leach DA, Zinonos I, Ponomarev V, Licari G, Liapis V, Ingman WV, Anderson P, DeNichilo MO, Evdokiou A.
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| Int J Oncol 50(4):1191-1200. doi: 10.3892/ijo.2017.3883. Epub 2017 Feb 20.
2017
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| 8 | MPO, PRTN3
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| Histone modification signature at myeloperoxidase and proteinase 3 in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis.
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| Yang J, Ge H, Poulton CJ, Hogan SL, Hu Y, Jones BE, Henderson CD, McInnis EA, Pendergraft WF 3rd, Jennette JC, Falk RJ, Ciavatta DJ.
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| Clin Epigenetics 8:85. doi: 10.1186/s13148-016-0251-0. eCollection 2016.
2016
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| 9 | CALR, MPO
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| Homozygous calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency.
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| Theocharides AP, Lundberg P, Lakkaraju AK, Lysenko V, Myburgh R, Aguzzi A, Skoda RC, Manz MG.
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| Blood 127(25):3253-9. doi: 10.1182/blood-2016-02-696310. Epub 2016 Mar 24.
2016
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| 10 | MPO
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| Myeloperoxidase negatively regulates the expression of proinflammatory cytokines and chemokines by zymosan-induced mouse neutrophils.
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| Endo D, Saito T, Umeki Y, Suzuki K, Aratani Y.
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| Inflamm Res 65(2):151-9. doi: 10.1007/s00011-015-0899-5. Epub 2015 Nov 14.
2016
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| 11 | MPO
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| Myeloperoxidase genetic polymorphisms and susceptibility to Kawasaki disease in Taiwanese children.
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| Weng KP, Hsieh KS, Huang SH, Wu HW, Chien JH, Lin CC, Tang CW, Ou SF, Huang SJ, Ger LP.
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| J Microbiol Immunol Infect 49(5):788-796. doi: 10.1016/j.jmii.2015.05.004. Epub 2015 May 14.
2016
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| 12 | EPX, MPO
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| Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.
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| Panagopoulos V, Zinonos I, Leach DA, Hay SJ, Liapis V, Zysk A, Ingman WV, DeNichilo MO, Evdokiou A.
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| Int J Biochem Cell Biol 68:128-38. doi: 10.1016/j.biocel.2015.09.006. Epub 2015 Sep 18.
2015
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| 13 | MPO
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| Myeloperoxidase-dependent lipid peroxidation promotes the oxidative modification of cytosolic proteins in phagocytic neutrophils.
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| Wilkie-Grantham RP, Magon NJ, Harwood DT, Kettle AJ, Vissers MC, Winterbourn CC, Hampton MB.
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| J Biol Chem 290(15):9896-905. doi: 10.1074/jbc.M114.613422. Epub 2015 Feb 19.
2015
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| 14 | MPO
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| Myeloperoxidase deletion prevents high-fat diet-induced obesity and insulin resistance.
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| Wang Q, Xie Z, Zhang W, Zhou J, Wu Y, Zhang M, Zhu H, Zou MH.
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| Diabetes 63(12):4172-85. doi: 10.2337/db14-0026. Epub 2014 Jul 14.
2014
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| 15 | MPO
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| Red blood cells serve as intravascular carriers of myeloperoxidase.
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| Adam M, Gajdova S, Kolarova H, Kubala L, Lau D, Geisler A, Ravekes T, Rudolph V, Tsao PS, Blankenberg S, Baldus S, Klinke A.
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| J Mol Cell Cardiol 74:353-63. doi: 10.1016/j.yjmcc.2014.06.009. Epub 2014 Jun 26.
2014
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| 16 | MPO
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| Myeloperoxidase in human intracranial aneurysms: preliminary evidence.
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| Gounis MJ, Vedantham S, Weaver JP, Puri AS, Brooks CS, Wakhloo AK, Bogdanov AA Jr.
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| Stroke 45(5):1474-7. doi: 10.1161/STROKEAHA.114.004956. Epub 2014 Apr 8.
2014
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| 17 | CFP, MPO
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| Myeloperoxidase directs properdin-mediated complement activation.
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| O'Flynn J, Dixon KO, Faber Krol MC, Daha MR, van Kooten C.
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| J Innate Immun 6(4):417-25. doi: 10.1159/000356980. Epub 2013 Dec 20.
2014
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| 18 | MPO
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| Inactivation of human myeloperoxidase by hydrogen peroxide.
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| Paumann-Page M, Furtmüller PG, Hofbauer S, Paton LN, Obinger C, Kettle AJ.
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| Arch Biochem Biophys 539(1):51-62. doi: 10.1016/j.abb.2013.09.004. Epub 2013 Sep 11.
2013
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| 19 | MPO, PON1
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| Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex.
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| Huang Y, Wu Z, Riwanto M, Gao S, Levison BS, Gu X, Fu X, Wagner MA, Besler C, Gerstenecker G, Zhang R, Li XM, DiDonato AJ, Gogonea V, Tang WH, Smith JD, Plow EF, Fox PL, Shih DM, Lusis AJ, Fisher EA, DiDonato JA, Landmesser U, Hazen SL.
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| J Clin Invest 123(9):3815-28. doi: 10.1172/JCI67478. Epub 2013 Aug 1.
2013
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| 20 | MPO
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| The potentiation of myeloperoxidase activity by the glycosaminoglycan-dependent binding of myeloperoxidase to proteins of the extracellular matrix.
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| Kubala L, Kolářová H, Víteček J, Kremserová S, Klinke A, Lau D, Chapman AL, Baldus S, Eiserich JP.
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| Biochim Biophys Acta 1830(10):4524-36. doi: 10.1016/j.bbagen.2013.05.024. Epub 2013 May 23.
2013
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| 21 | MPO
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| Neutrophil myeloperoxidase regulates T-cell-driven tissue inflammation in mice by inhibiting dendritic cell function.
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| Odobasic D, Kitching AR, Yang Y, O'Sullivan KM, Muljadi RC, Edgtton KL, Tan DS, Summers SA, Morand EF, Holdsworth SR.
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| Blood 121(20):4195-204. doi: 10.1182/blood-2012-09-456483. Epub 2013 Mar 18.
2013
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| 22 | CP, MPO
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| Ceruloplasmin is an endogenous inhibitor of myeloperoxidase.
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| Chapman AL, Mocatta TJ, Shiva S, Seidel A, Chen B, Khalilova I, Paumann-Page ME, Jameson GN, Winterbourn CC, Kettle AJ.
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| J Biol Chem 288(9):6465-77. doi: 10.1074/jbc.M112.418970. Epub 2013 Jan 10.
2013
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| 23 | MPO
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| Myeloperoxidase is an early biomarker of inflammation and cardiovascular risk in prepubertal obese children.
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| Olza J, Aguilera CM, Gil-Campos M, Leis R, Bueno G, Martínez-Jiménez MD, Valle M, Cańete R, Tojo R, Moreno LA, Gil A.
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| Diabetes Care 35(11):2373-6. doi: 10.2337/dc12-0614. Epub 2012 Aug 21.
2012
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| 24 | MPO
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| Functional consequence of positive selection revealed through rational mutagenesis of human myeloperoxidase.
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| Loughran NB, Hinde S, McCormick-Hill S, Leidal KG, Bloomberg S, Loughran ST, O'Connor B, O'Fágáin C, Nauseef WM, O'Connell MJ.
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| Mol Biol Evol 29(8):2039-46. doi: 10.1093/molbev/mss073. Epub 2012 Feb 21.
2012
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| 25 | MPO
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| Association of the 463G-A myeloperoxidase gene polymorphism with gastric cancer risk.
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| Jiang Z, Zhang Z, Wang Z, Zhang G, Hu K, He B, Wang S.
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| Hepatogastroenterology 59(115):757-61. doi: 10.5754/hge11054.
2012
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| 26 | MPO
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| Plasma myeloperoxidase level and peripheral arterial disease.
|
| Haslacher H, Perkmann T, Gruenewald J, Exner M, Endler G, Scheichenberger V, Wagner O, Schillinger M.
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| Eur J Clin Invest 42(5):463-9. doi: 10.1111/j.1365-2362.2011.02601.x. Epub 2011 Sep 23.
2012
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| 27 | MPO
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| Intriguing location of myeloperoxidase in the prostate: a preliminary immunohistochemical study.
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| Roumegučre T, Delree P, Van Antwerpen P, Rorive S, Vanhamme L, de Ryhove Lde L, Serteyn D, Wespes E, Vanhaerverbeek M, Boudjeltia KZ.
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| Prostate 72(5):507-13. doi: 10.1002/pros.21452. Epub 2011 Jul 7.
2012
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| 28 | MPO
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| Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity.
|
| Metzler KD, Fuchs TA, Nauseef WM, Reumaux D, Roesler J, Schulze I, Wahn V, Papayannopoulos V, Zychlinsky A.
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| Blood 117(3):953-9. doi: 10.1182/blood-2010-06-290171. Epub 2010 Oct 25.
2011
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| 29 | MPO
|
| Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
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| Rudolph V, Andrié RP, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer AP, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner EC, Szoecs K, Schrickel JW, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann WH, Meinertz T, Böger RH, Reichenspurner H, Freeman BA, Eschenhagen T, Ehmke H, Hazen SL, Willems S, Baldus S.
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| Nat Med 16(4):470-4. Epub 2010 Mar 21.
2010
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| 30 | MPO, SFTPD
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| Myeloperoxidase-dependent inactivation of surfactant protein D in vitro and in vivo.
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| Crouch EC, Hirche TO, Shao B, Boxio R, Wartelle J, Benabid R, McDonald B, Heinecke J, Matalon S, Belaaouaj A.
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| J Biol Chem 285(22):16757-70. Epub 2010 Mar 12.PMID: 20228064 2010
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| 31 | MPO, ZNF296
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| Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23;q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia.
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| Poland KS, Shardy DL, Azim M, Naeem R, Krance RA, Dreyer ZE, Neeley ES, Zhang N, Qiu YH, Kornblau SM, Plon SE.
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| Genes Chromosomes Cancer 48(6):480-9.
2009
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| 32 | MPO
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| Essential role of proximal histidine-asparagine interaction in mammalian peroxidases.
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| Carpena X, Vidossich P, Schroettner K, Calisto BM, Banerjee S, Stampler J, Soudi M, Furtmüller PG, Rovira C, Fita I, Obinger C.
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| J Biol Chem 284(38):25929-37. Epub 2009 Jul 16.PMID: 19608745 2009
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| 33 | MPO
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| Myeloperoxidase overexpression in children with hypercholesterolemia.
|
| Pignatelli P, Loffredo L, Martino F, Catasca E, Carnevale R, Zanoni C, Del Ben M, Antonini R, Basili S, Violi F.
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| Atherosclerosis 205(1):239-43. Epub 2008 Nov 6.PMID: 19081093 2009
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| 34 | MPO
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| Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure.
|
| La Rocca G, Di Stefano A, Eleuteri E, Anzalone R, Magno F, Corrao S, Loria T, Martorana A, Di Gangi C, Colombo M, Sansone F, Patanč F, Farina F, Rinaldi M, Cappello F, Giannuzzi P, Zummo G.
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| Basic Res Cardiol 104(3):307-20. Epub 2008 Nov 22.PMID: 19030913 2009
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| 35 | CP, MPO
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| Ceruloplasmin and myeloperoxidase in complex affect the enzymatic properties of each other.
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| Sokolov AV, Ageeva KV, Pulina MO, Cherkalina OS, Samygina VR, Vlasova II, Panasenko OM, Zakharova ET, Vasilyev VB.
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| Free Radic Res 42(11-12):989-98.PMID: 19031316 2008
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| 36 | MPO, MPOD
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| Impact of two novel mutations on the structure and function of human myeloperoxidase.
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| Goedken M, McCormick S, Leidal KG, Suzuki K, Kameoka Y, Astern JM, Huang M, Cherkasov A, Nauseef WM.
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| J Biol Chem 282(38):27994-8003. Epub 2007 Jul 24. 2007
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| 37 | MPO, NR1H3, PPARA
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| The human myeloperoxidase gene is regulated by LXR and PPARalpha ligands.
|
| Reynolds WF, Kumar AP, Piedrafita FJ.
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| Biochem Biophys Res Commun 349(2):846-54. Epub 2006 Aug 31. 2006
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| 38 | EPX, MPO
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| Thiocyanate modulates the catalytic activity of mammalian peroxidases.
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| Tahboub YR, Galijasevic S, Diamond MP, Abu-Soud HM.
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| J Biol Chem 280(28):26129-36. Epub 2005 May 13.
2005
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| 39 | CYP2E1, MPO, NQO1
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| Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.
|
| Krajinovic M, Sinnett H, Richer C, Labuda D, Sinnett D.
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| Int J Cancer 97(2):230-6. 2002
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| 40 | EPX, LPO, MPO, EPXD
|
| The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.
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| Sakamaki K, Kanda N, Ueda T, Aikawa E, Nagata S.
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| Cytogenet Cell Genet 88(3-4):246-8. 2000
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| 41 | MPO
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| Molecular analysis of the human myeloperoxidase promoter region.
|
| Chumakov AM, Chumakova EA, Chih D, Koeffler HP.
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| Int J Oncol 16(2):401-11. 2000
|
| 42 | MPO, MPOD
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| A novel form of hereditary myeloperoxidase deficiency linked to endoplasmic reticulum/proteasome degradation.
|
| DeLeo FR, et al.
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| J Clin Invest 101 : 2900-2909. 1998
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| 43 | MPO, MPOD
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| Biochemical and molecular characterization of hereditary myeloperoxidase deficiency.
|
| Romano M, Dri P, Dadalt L, Patriarca P, Baralle FE.
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| Blood 90(10):4126-34. 1997
|
| 44 | EPO, LPO, MPO
|
| Molecular cloning and characterization of the chromosomal gene for human lactoperoxidase.
|
| Ueda T, Sakamaki K, Kuroki T, Yano I, Nagata S.
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| Eur J Biochem 243(1-2):32-41. 1997
|
| 45 | TRIM25, MPO
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| Localization of the human estrogen-responsive finger protein (EFP) gene (ZNF147) within a YAC contig containing the myeloperoxidase (MPO) gene.
|
| Law DJ, et al.
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| Genomics 28 : 361-363. 1995
|
| 46 | MPO, MPOD
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| Hereditary myeloperoxidase deficiency due to a missense mutation of arginine 569 to tryptophan.
|
| Nauseef WM, et al.
|
| J Biol Chem 269 : 1212-1216. 1994
|
| 47 | MPO
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| Dinucleotide repeat polymorphism at the human gene of the light and heavy chains of myeloperoxidase glycoprotein (MPO).
|
| Polymeropoulos MH, et al.
|
| Nucleic Acids Res 19 : 1961. 1991
|
| 48 | MPO
|
| A KpnI RFLP at the human myeloperoxidase locus.
|
| Sanchez I, et al.
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| Nucleic Acids Res 19 : 3763. 1991
|
| 49 | MPO, PRKCA, D17S61
|
| Refinement of localization of the human genes for myeloperoxidase (MPO), protein kinase C, alpha polypeptide, PRKCA, and the DNA fragment D17S21 on chromosome 17q.
|
| Latos-Bielenska A, et al.
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| Hereditas 115 : 69-72. 1991
|
| 50 | MPO
|
| Chromosomal localization of the human myeloperoxidase gene by in situ hybridization using oligonucleotide probes.
|
| Zaki SR, et al.
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| Genes Chromosomes Cancer 2 : 266-270. 1990
|
| 51 | MPO
|
| A myeloperoxidase cDNA clone identifies an EcoRV RFLP.
|
| Tobler A, et al.
|
| Nucleic Acids Res 18 : 6176. 1990
|
| 52 | MPO
|
| Assignment of the human myeloperoxidase gene (MPO) to bands q21.3----q23 of chromosome 17.
|
| Inazawa J, Inoue K, Nishigaki H, Tsuda S, Taniwaki M, Misawa S, Abe T.
|
| Cytogenet Cell Genet 50 : 135-136. 1989
|
| 53 | MPO
|
| Evidence for a pretranslational defect in hereditary and acquired myeloperoxidase deficiency.
|
| Tobler A, et al.
|
| Blood 73 : 1980-1986. 1989
|
| 54 | MPO
|
| Assignment of the human myeloperoxidase gene to q21.3-q23 Bands of chromosome 17.
|
| Abe T, et al.
|
| (HGM10) Cytogenet Cell Genet 51 : 948. 1989
|
| 55 | MPO
|
| The myeloperoxidase gene in acute promyelocytic leukemia.
|
| Miller CW, et al.
|
| Science 244 : 823-826. 1989
|
| 56 | MPO
|
| An MPO cDNA clone identifies an RFLP with PstI.
|
| Miki T, et al.
|
| Nucleic Acids Res 16 : 1649. 1988
|
| 57 | MPO
|
| Translocation and rearrangement of myeloperoxidase gene in acute promyelocytic leukemia.
|
| Weil SC, et al.
|
| Science 240 : 790-792. 1988
|
| 58 | MPO
|
| Chromosomal localization of the gene encoding myeloperoxidase.
|
| Le Beau MM, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 645. 1987
|
| 59 | MPO
|
| The localization of human myeloperoxidase gene is in close proximity to the translocation breakpoint in acute promyelocytic leukemia.
|
| Chang KS, et al.
|
| Leukemia 1 : 458-462. 1987
|
| 60 | MPO
|
| Assignment of the myeloperoxidase (MPO) gene to human chromosome 17.
|
| Kudoh J, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 641. 1987
|
| 61 | MPO
|
| cDNA cloning of human myeloperoxidase : Decrease in myeloperoxidase mRNA upon induction of HL-60 cells.
|
| Weil SC, et al.
|
| Proc Natl Acad Sci U S A 84 : 2057-2061. 1987
|
| 62 | MPO
|
| Leukocyte myeloperoxidase deficiency and disseminated candidiasis : the role of myeloperoxidase in resistance to candida infection.
|
| Lehrer RI, et al.
|
| J Clin Invest 48 : 1478-1488. 1969
|