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FLASH GENE

Symbol

SLC9A1

contributors: mct/ - updated : 01-02-2013

HGNC name	solute carrier family 9 (sodium/hydrogen exchanger), member 1
HGNC id	11071

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SCAR19

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional germinal mutation       in slow-wawe epilepsy constitutional       gain of function is sufficient to initiate cardiac hypertrophy and heart failure mainly through activation of CaMKII-histone deacetylase pathway tumoral       gain of function promote metastasis in human mammary epithelial cells

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS