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FLASH GENE
Symbol IFT88 contributors: npt/mct - updated : 07-09-2017
HGNC name intraflagellar transport 88 homolog (Chlamydomonas)
HGNC id 20606
ANIMAL & CELL MODELS
  • transgenic mice containing an insertional mutation in Tg373 (Moyer,94)
  • C. elegans daf-19 mutant worms can thus serve as a molecular model for the mechanisms of functional neuronal decline seen in many human neurodegenerative disorders (Senti 2008)
  • spermatids of the Ift88 mouse mutant display abnormal head shaping and are tail-less
  • Ift88(-/-) mice are completely sterile