| 1 | IFT20, IFT88, MEIG1
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| MEIG1 determines the manchette localization of IFT20 and IFT88, two intraflagellar transport components in male germ cells
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| Yap YT, Shi L, Zhang D, Huang Q, Siddika F, Wang Z, Li W, Zhang Z.
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| Dev Biol. May;485:50-60. doi: 10.1016/j.ydbio.2022.03.001. Epub 2022 Mar 4. 2022
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| 2 | IFT20, IFT57, IFT88
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| The T cell IFT20 interactome reveals new players in immune synapse assembly.
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| Galgano D, Onnis A, Pappalardo E, Galvagni F, Acuto O, Baldari CT.
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| J Cell Sci 130(6):1110-1121. doi: 10.1242/jcs.200006. Epub 2017 Feb 2.
2017
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| 3 | IFT88
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| IFT88 influences chondrocyte actin organization and biomechanics.
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| Wang Z, Wann AK, Thompson CL, Hassen A, Wang W, Knight MM.
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| Osteoarthritis Cartilage 24(3):544-54. doi: 10.1016/j.joca.2015.10.003. Epub 2015 Oct 19.
2016
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| 4 | IFT88, KIF3A
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| Heterotrimeric kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptors.
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| Jiang L, Wei Y, Ronquillo CC, Marc RE, Yoder BK, Frederick JM, Baehr W.
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| J Biol Chem 290(20):12765-78. doi: 10.1074/jbc.M115.638437. Epub 2015 Mar 30.
2015
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| 5 | IFT88
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| A Cilia Independent Role of Ift88/Polaris during Cell Migration.
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| Boehlke C, Janusch H, Hamann C, Powelske C, Mergen M, Herbst H, Kotsis F, Nitschke R, Kuehn EW.
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| PLoS One 10(10):e0140378. doi: 10.1371/journal.pone.0140378. eCollection 2015.
2015
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| 6 | IFT88
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| Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm.
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| San Agustin JT, Pazour GJ, Witman GB.
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| Mol Biol Cell 26(24):4358-72. doi: 10.1091/mbc.E15-08-0578. Epub 2015 Sep 30.
2015
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| 7 | IFT88, TGFB1
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| TGF-β Suppresses Ift88 Expression in Chondrocytic ATDC5 Cells.
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| Kawasaki M, Ezura Y, Hayata T, Notomi T, Izu Y, Noda M.
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| J Cell Physiol 230(11):2788-95. doi: 10.1002/jcp.25005.
2015
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| 8 | IFT88, MYH10
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| Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia.
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| Hong H, Kim J, Kim J.
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| Biochem Biophys Res Commun 461(1):180-5. doi: 10.1016/j.bbrc.2015.04.028. Epub 2015 Apr 13.
2015
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| 9 | C2CD3, IFT52, IFT88
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| C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
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| Ye X, Zeng H, Ning G, Reiter JF, Liu A.
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| Proc Natl Acad Sci U S A 111(6):2164-9. doi: 10.1073/pnas.1318737111. Epub 2014 Jan 27. 2014
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| 10 | IFT88, SFRP5
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| Ift88 regulates Hedgehog signaling, Sfrp5 expression, and β-catenin activity in post-natal growth plate.
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| Chang CF, Serra R.
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| J Orthop Res 31(3):350-6. doi: 10.1002/jor.22237. Epub 2012 Oct 3.
2013
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| 11 | IFT88
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| Tg737 inhibition results in malignant transformation in fetal liver stem/progenitor cells by promoting cell-cycle progression and differentiation arrest.
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| You N, Liu W, Zhong X, Ji R, Zhang M, You H, Dou K, Tao K.
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| Mol Carcinog 51(8):659-73. doi: 10.1002/mc.20839. Epub 2011 Aug 11. Erratum in: Mol Carcinog. 2012 Oct;51(10):843.
2012
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| 12 | IFT88
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| The cilia protein IFT88 is required for spindle orientation in mitosis.
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| Delaval B, Bright A, Lawson ND, Doxsey S.
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| Nat Cell Biol 13(4):461-8. doi: 10.1038/ncb2202. Epub 2011 Mar 27.
2011
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| 13 | IFT88, TRIP11
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| GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail.
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| Kierszenbaum AL, Rivkin E, Tres LL, Yoder BK, Haycraft CJ, Bornens M, Rios RM.
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| Dev Dyn 240(3):723-36. doi: 10.1002/dvdy.22563. Epub 2011 Feb 10.
2011
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| 14 | IFT46, IFT52, IFT88
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| Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46.
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| Lucker BF, Miller MS, Dziedzic SA, Blackmarr PT, Cole DG.
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| J Biol Chem 285(28):21508-18. doi: 10.1074/jbc.M110.106997. Epub 2010 Apr 30.
2010
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| 15 | IFT172, IFT57, IFT88
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| Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling.
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| Lunt SC, Haynes T, Perkins BD.
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| Dev Dyn 238(7):1744-59. doi: 10.1002/dvdy.21999.
2009
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| 16 | IFT88
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| Ciliary proteins link basal body polarization to planar cell polarity regulation.
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| Jones C, Roper VC, Foucher I, Qian D, Banizs B, Petit C, Yoder BK, Chen P.
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| Nat Genet 40(1):69-77. Epub 2007 Dec 9. 2008
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| 17 | IFT88, RFX3
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| Distinct isoforms of the RFX transcription factor DAF-19 regulate ciliogenesis and maintenance of synaptic activity.
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| Senti G, Swoboda P.
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| Mol Biol Cell 19(12):5517-28. Epub 2008 Oct 8. 2008
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| 18 | IFT88
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| The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells.
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| Robert A, Margall-Ducos G, Guidotti JE, Brégerie O, Celati C, Bréchot C, Desdouets C.
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| J Cell Sci 120(Pt 4):628-37. Epub 2007 Jan 30. Erratum in: J Cell Sci. 2007 Mar 1;120(Pt 5):918.
2007
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| 19 | OFD1, IFT172, IFT88
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| Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification.
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| Ferrante MI, Zullo A, Barra A, Bimonte S, Messaddeq N, Studer M, Dolle P, Franco B.
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| Nat Genet 38(1):112-7. Epub 2005 Nov 27. 2006
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| 20 | BTRC, CREBBP, CSRP2, FKBP8, GAS1, GSK3B, HHAT, HHIP, IFT88, KIF27, KIF3A, KIF7, RAB23, SHH, STIL, STK36, SUFU, VTN
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| Hedgehog signaling and congenital malformations.
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| Nieuwenhuis E, Hui CC.
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| Clin Genet 67(3):193-208. 2005
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| 21 | TSG13D, LATS2, CRYL1, IFT88, GJB2
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| Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11.
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| Chen CF, Yeh SH, Chen DS, Chen PJ, Jou YS.
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| Genes Chromosomes Cancer 44(3):320-8. 2005
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| 22 | IFT88
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| Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia.
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| Taulman PD, Haycraft CJ, Balkovetz DF, Yoder BK.
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| Mol Biol Cell 12(3):589-99.
2001
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| 23 | IFT88
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| Structure and expression of Tg737, a putative tumor suppressor gene, in human hepatocellular carcinomas.
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| Bonura C, Paterlini-Brechot P, Brechot C.
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| Hepatology 30(3):677-81 1999
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| 24 | IFT88, TSG13D
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| The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene.
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| Isfort RJ, Cody DB, Doersen CJ, Richards WG, Yoder BK, Wilkinson JE, Kier LD, Jirtle RL, Isenberg JS, Klounig JE, Woychik RP.
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| Oncogene 15(15):1797-803. 1997
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| 25 | IFT88
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| Characterization of the human homologue of the mouse Tg737 candidate polycystic kidney disease gene.
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| Schrick JJ, et al.
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| Hum Mol Genet 4 : 559-567. 1995
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| 26 | IFT88
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| Sequence analysis of the human hTg737 gene and its polymorphic sites in patients with autosomal recessive polycystic kidney disease.
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| Onuchic LF, et al.
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| Mamm Genome 6 : 805-808. 1995
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| 27 | ARPKD, IFT88
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| Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.
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| Moyer JH, Lee-Tischler MJ, Kwon HY, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NL, Wilkinson JE, Woychik RP.
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| Science 264(5163):1329-33. 1994
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