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FLASH GENE

Symbol

RUNX3

contributors: mct - updated : 24-03-2017

HGNC name	runt-related transcription factor 3
HGNC id	10473

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Runx3 +/- mice develop lung adenomas spontaneously, providing an animal model for lung tumorigenesis that recapitulate the preneoplastic stage of human lung adenocarcinoma development
	Runx3-deficient mice develop severe congenital osteopenia