protein
| RB, CENPE, BUB1B |
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may be a negative regulator of ATF4 in interphase through direct interaction |
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PARP1 interaction with CENPB, CENPE, and CENPF during mitosis and apoptosis |
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interacting with E2F5 (CENPF translocation to the nucleus is an important first step during entry into quiescence) |
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HOOK2 is a binding partner of CENPF |
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major function of CENPF, is to link the NDEL1/NDE1/PAFAH1B1/Dynein pathway to kinetochores (NDEL1 and NDE1 play distinct roles to ensure chromosome alignment and segregation) |
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critical for myocyte differentiation through the interaction with RB, and binds to ATF4 and negatively regulates the transcriptional activity of ATF4 |
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associated with the DNA-dependent protein kinase (PRKDC), a trimeric protein complex critical for genome homeostasis |
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CENPF is recruited to mitochondria by RHOT1 at the time of cytokinesis and associates with microtubule growing tips |
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CHAMP1 regulates localization of CENPE and CENPF to kinetochores |
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SYCP2 N-reminal region interacts with the centromere during meiosis I, with CENPJ and CENPF |
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NUP133 interacts with CENPF both at nuclear pores in prophase and at kinetochores in mitosis |