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FLASH GENE
Symbol H2AFX contributors: mct/pgu - updated : 07-04-2016
HGNC name H2A histone family, member X
HGNC id 4739
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
vascular-targeted inhibitors of H2AFX may provide a new strategy for preventing hypoxia-induced pathological neovascularization in conditions such as in tumor growth
neurosensorialvisualdegenerative
vascular-targeted inhibitors of H2AFX may provide a new strategy for preventing hypoxia-induced pathological neovascularization in conditions such as retinopathy of prematurity or diabetic retinopathy
ANIMAL & CELL MODELS
H2AX-/- mice